Gene Information

Name : set8 (SA0384)
Accession : NP_373634.1
Strain : Staphylococcus aureus N315
Genome accession: NC_002745
Putative virulence/resistance : Virulence
Product : superantigen-like protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG3889
EC number : -
Position : 443054 - 444124 bp
Length : 1071 bp
Strand : +
Note : these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation

DNA sequence :
ATGAATATGAAAACAATTGCTAAAACCAGTTTAGCACTAGGGCTTTTAACAACAGGCGCAATTACAGTAACGACGCAATC
GGTCAAAGCAGAAAAAATACAATCAACTAAAGTTGACAAAGTACCAACGCTTAAAGCAGAGCGATTAGCAATGATAAACA
TAACAGCAGGTGCAAATTCAGCGACAACACAAGCAGCTAACACAAGACAAGAACGCACGCCTAAACTCGAAAAGGCACCA
AATACTAATGAGGAAAAAACCTCAGCTTCCAAAATAGAAAAAATATCACAACCTAAACAAGAAGAGCAGAAATCGCTTAA
TATATCAGCAACGCCAGCGCCTAAACAAGAACAATCACAAACGACAACCGAATCCACAACGCCGAAAACTAAAGTGACAA
CACCTCCATCAACAAACACGCCACAACCAATGCAATCTACTAAATCAGACACACCACAATCTCCAACCATAAAACAAGCA
CAAACAGATATGACTCCTAAATATGAAGATTTAAGAGCGTATTACACGAAACCGAGTTTTGAATTTGAAAAGCAGTTTGG
ATTTTTGCTCAAACCATGGACGACGGTTAGGTTTATGAATGTTATTCCAAATAGGTTCATCTATAAAATAGCTTTAGTTG
GAAAAGATGAGAAAAAATATAAAGATGGACCTTACGATAATATCGATGTATTTATCGTTTTAGAAGACAATAAATATCAA
TTAAAAAAATATTCTGTCGGTGGCATCACGAAGACTAATAGTAAAAAAGTTGATCACAAAGCAGAATTAAGCGTTACTAA
AAAAGATAATCAAGGTATGATTTCACGCGATGTTTCAGAATACATGATTACTAAGGAAGAGATTTCCTTGAAAGAGCTTG
ATTTTAAATTGAGAAAACAACTTATTGAAAAACATAATCTTTACGGTAACATGGGTTCAGGAACAATCGTTATTAAAATG
AAAAACGGTGGGAAGTATACGTTTGAATTACACAAAAAACTGCAAGAGCATCGTATGGCAGATGTCATAGAAGGTACAAA
CATTGATAAAATTGAAGTGAATATAAAATAA

Protein sequence :
MNMKTIAKTSLALGLLTTGAITVTTQSVKAEKIQSTKVDKVPTLKAERLAMINITAGANSATTQAANTRQERTPKLEKAP
NTNEEKTSASKIEKISQPKQEEQKSLNISATPAPKQEQSQTTTESTTPKTKVTTPPSTNTPQPMQSTKSDTPQSPTIKQA
QTDMTPKYEDLRAYYTKPSFEFEKQFGFLLKPWTTVRFMNVIPNRFIYKIALVGKDEKKYKDGPYDNIDVFIVLEDNKYQ
LKKYSVGGITKTNSKKVDHKAELSVTKKDNQGMISRDVSEYMITKEEISLKELDFKLRKQLIEKHNLYGNMGSGTIVIKM
KNGGKYTFELHKKLQEHRMADVIEGTNIDKIEVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
set8 NP_370948.1 superantigen-like protein Virulence vSa¥á Protein 1e-139 100
set8 NP_373634.1 superantigen-like protein Virulence vSa¥á Protein 1e-139 100
SACOL0470 YP_185360.1 superantigen-like protein Virulence vSa¥á Protein 2e-134 97
set3nm YP_001331424.1 superantigen-like protein Virulence vSa¥á Protein 2e-134 97
SAUSA300_0397 YP_493111.1 superantigen-like protein Virulence vSa¥á Protein 2e-134 97
SAS0386 YP_042511.1 superantigen-like protein Virulence vSa¥á Protein 2e-138 97
set18 NP_645201.1 superantigen-like protein Virulence vSa¥á Protein 1e-138 97
SAKOR_00406 YP_008490590.1 Exotoxin Virulence vSa¥á Protein 2e-135 95
SAR0425 YP_039877.1 superantigen-like protein Not tested vSa¥á Protein 3e-91 65
SAMSHR1132_03740 YP_005324896.1 exotoxin Virulence vSa¥á Protein 1e-87 63
SAR0424 YP_039876.1 superantigen-like protein Virulence vSa¥á Protein 3e-84 55