Gene Information

Name : arsC (SPy_0891)
Accession : NP_269090.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Resistance
Product : arsenate reductase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1393
EC number : -
Position : 739233 - 739673 bp
Length : 441 bp
Strand : +
Note : Best Blastp hit = sp|P52147|ARC2_ECOLI ARSENATE REDUCTASE (ARSENICAL PUMP MODIFIER) >gi|1061418|gb|AAB09628.1| (U38947) ArsC [Plasmid R46]

DNA sequence : 
ATGGAAGAAATCACGATTTATCATAATCCAAACTGTGGCACTTCACGTAATGTTCTTGCCATGATTCGCCATGCAGGTAT
TGAGCCTACTATTATTGAGTATTTGCAGACGCCACCTAATCGGGAGACTTTAATTGAGCTCTTACAATCGATGGGAATCT
CTGCAAGAGAACTCTTGCGAACCAATGTTCCTGAATTTGAGGCTTATGGATTAGCAAATCAAGCAGTAGCTGAGAAAGAC
ATTATTAATGCCATGTTGGCGGATCCAATTTTGATCAATCGTCCTATTGTTGTGACTCGCAAAGGAGTAAAACTTTGCCG
TCCTTCTGAGACCTTACTGGATATTCTTCCTGTTCCCCTGCCTAGTCCTTATATTAAAGAGGATGGCGAGAGTGTGAACC
CTATTGAGGTAAAAGGAGAAAAAGATGTCATTGATGACTAA

Protein sequence : 
MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLIELLQSMGISARELLRTNVPEFEAYGLANQAVAEKD
IINAMLADPILINRPIVVTRKGVKLCRPSETLLDILPVPLPSPYIKEDGESVNPIEVKGEKDVIDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC2 YP_001007634.1 arsenate reductase Not tested YAPI Protein 7e-35 57
arsC ADZ05768.1 arsenate reductase Not tested AbaR11 Protein 6e-31 49
arsR CAJ77019.1 arsenate reductase Not tested AbaR1 Protein 8e-31 49
arsC AFC76436.1 ArsC Not tested AbaR5 Protein 1e-30 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsC NP_269090.1 arsenate reductase BAC0583 Protein 1e-37 60
arsC NP_269090.1 arsenate reductase BAC0582 Protein 3e-36 58
arsC NP_269090.1 arsenate reductase BAC0585 Protein 1e-36 57
arsC NP_269090.1 arsenate reductase BAC0584 Protein 8e-37 57