Gene Information

Name : mtsA (SPy_0453)
Accession : NP_268747.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Virulence
Product : ABC transporter metal binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 371477 - 372409 bp
Length : 933 bp
Strand : +
Note : Best Blastp hit = pir||T48894 lipoprotein mtsA, metal binding [validated] - Streptococcus pyogenes (fragment) >gi|5932388|gb|AAD56939.1|AF180521_1 (AF180521) metal binding protein of ABC transporter MtsA [Streptococcus pyogenes]

DNA sequence :
ATGGGAAAGAGAATGAGCCTCATTTTGGGTGCTTTTTTATCTGTTTTTCTTTTAGTAGCTTGTTCGTCAACTGGCACTAA
AACTGCTAAGAGTGATAAATTAAAAGTCGTGGCAACCAATTCAATTATTGCCGACATGACAAAAGCTATTGCTGGTGATA
AAATCGATCTGCACAGCATTGTGCCAATCGGTCAAGACCCTCATGAGTACGAACCATTACCAGAAGATGTTGAAAAAACA
AGTAATGCTGATGTGATTTTCTATAATGGTATCAATCTAGAAGATGGCGGGCAAGCTTGGTTCACCAAACTAGTGAAAAA
TGCTCAAAAAACGAAAAACAAAGATTACTTTGCCGTGTCTGATGGCATTGATGTGATTTACTTGGAAGGTGCAAGCGAAA
AAGGAAAAGAAGATCCACATGCTTGGTTAAATCTCGAAAACGGAATCATTTATTCAAAAAACATTGCCAAACAATTGATT
GCAAAGGATCCTAAAAACAAAGAAACTTATGAAAAGAACCTAAAAGCTTATGTGGCTAAATTGGAAAAACTAGACAAAGA
AGCCAAATCAAAATTTGATGCTATTGCAGAAAATAAAAAATTGATTGTGACTAGTGAAGGCTGCTTCAAGTACTTTTCAA
AAGCTTACGGTGTCCCATCTGCTTATATCTGGGAAATTAACACCGAAGAAGAAGGAACACCAGATCAAATTTCATCATTG
ATTGAAAAACTAAAAGTCATCAAGCCATCTGCGCTTTTTGTAGAGTCAAGTGTCGATAGACGCCCTATGGAAACTGTTTC
TAAAGATAGTGGTATTCCTATTTATTCTGAGATCTTTACAGATTCAATTGCTAAAAAAGGTAAACCTGGCGATAGTTATT
ATGCTATGATGAAATGGAACCTTGACAAAATTTCTGAAGGTCTAGCAAAATAA

Protein sequence :
MGKRMSLILGAFLSVFLLVACSSTGTKTAKSDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEGASEKGKEDPHAWLNLENGIIYSKNIAKQLI
AKDPKNKETYEKNLKAYVAKLEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEEEGTPDQISSL
IEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFTDSIAKKGKPGDSYYAMMKWNLDKISEGLAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ef0095 AAM75298.1 EF0095 Not tested Not named Protein 2e-106 73
EF0577 NP_814342.1 adhesion lipoprotein Virulence Not named Protein 3e-106 73

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mtsA NP_268747.1 ABC transporter metal binding protein VFG1359 Protein 8e-113 77
mtsA NP_268747.1 ABC transporter metal binding protein VFG2165 Protein 1e-86 57
mtsA NP_268747.1 ABC transporter metal binding protein VFG2157 Protein 1e-77 50