Gene Information

Name : fhuA (SPy_0386)
Accession : NP_268706.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Virulence
Product : ferrichrome ABC transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 329587 - 330369 bp
Length : 783 bp
Strand : -
Note : Best Blastp hit = gb|AAD33527.2|AF132117_4 (AF132117) FhuA [Staphylococcus aureus] >gi|9755013|gb|AAF98153.1|AF251216_1 (AF251216) FhuC [Staphylococcus aureus]

DNA sequence : 
ATGACAACAATTAGTGCTGAAGACCTCACAATTGCCTATGAACAGCGTACCATCATCGATAAATTATCGTTTTATATTCC
TGAAGGTAAAATTACGACCATTATTGGCGCCAATGGCTGTGGGAAGTCTAGTTTATTAAAAGCACTGACAAGATTATTAC
CACCAAAACAGGGAGTTGTATATTTAAATGGGCAAAACATTGCCACATTAGAAACTAAAGAGGTTGCTAAAAAACTAGCT
CTTTTACCTCAAGTTCAAGAAGCAACTAACGGCATAACTGTTTACGAATTGGTTTCTTACGGACGTTTTCCCCATCAATC
TTACTTTGGAAATCTTAGTCCAGCTGACAAAAAAGCCATTCATTGGGCTATGCAAGCCACCAATGTCATGGCCTATGCTG
ATCAACCTGTTGATGCTCTTTCTGGGGGGCAACGTCAAAGGGTTTGGCTTGCAATGGCATTAGCCCAAGGCACTGATACT
ATTTTTTTAGATGAGCCAACTACTTATTTAGATTTAAATCATCAACTAGAAATCCTAGAGCTCGTTAAATCCCTAAATAA
GGATGCCGGCAAGACTATTGTTATGGTTCTTCACGACCTCAATCTTTCAGCCCGCTATTCGGATCATCTGATTGCTATGA
AACATGGCAAGATCCATTATACTGGTACTATAGCAGATGTTATGACTTCACCTATCATTCAAGACATCTTCCAAATCAAA
CCGGTACTGGTTGATGATCCTATCCACAACTGTCCTATAGTGCTGACTTATCAGCTTCAATAA

Protein sequence : 
MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLA
LLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKAIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIK
PVLVDDPIHNCPIVLTYQLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-58 47
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 2e-58 47
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-58 47
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-58 47
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 6e-59 46
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-53 45
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-53 45
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-50 45
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-52 44
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-51 43
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-51 43
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-51 43
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 6e-51 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuA NP_268706.1 ferrichrome ABC transporter ATP-binding protein BAC0164 Protein 1e-52 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuA NP_268706.1 ferrichrome ABC transporter ATP-binding protein VFG0925 Protein 3e-58 46
fhuA NP_268706.1 ferrichrome ABC transporter ATP-binding protein VFG1042 Protein 9e-53 44