Gene Information

Name : hasC.2 (SPy_0224)
Accession : NP_268587.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Virulence
Product : UDP-glucose pyrophosphorylase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1210
EC number : 2.7.7.9
Position : 197663 - 198562 bp
Length : 900 bp
Strand : -
Note : Best Blastp hit = emb|CAB90754.1| (AJ400707) UDP-glucose pyrophosphorylase [Streptococcus uberis]

DNA sequence :
ATGACCAAAGTCAGAAAAGCTATTATTCCCGCAGCAGGTTTAGGCACACGTTTTTTACCTGCAACCAAGGCCCTTGCCAA
GGAGATGCTACCTATTGTTGATAAACCAACTATTCAATTTATCGTTGAAGAAGCTCTAAAATCAGGTATCGAAGAAATTC
TTATCGTTACTGGAAAATCCAAACGCTCCATAGAAGATCATTTTGATTCTAATTTTGAATTAGAATATAATTTACAGGCT
AAAGGAAAAATCGAACTTCTAAAGTTAGTAGACGAGACCACTTCTATTAATCTTCACTTTATTCGACAGAGTCATCCAAG
AGGATTAGGAGACGCAGTTCTTCAAGCAAAGACCTTTGTTGGCAATGAACCTTTTGTTGTCATGCTAGGTGATGATCTGA
TGGATATTACAAATCCAAATGTAAAACCATTAACCAAACAATTGATCGATGACTATGAAGAAACTCATGCTGCAACTATT
GCCGTCATGAGGGTTCCTCACGAGGATGTCTCTAACTACGGTATCATTGCTCCTCAAGCAAAAGCAGTAAAAGGACTCTA
TAGTGTGGATACTTTTGTTGAAAAACCACAACCTCAAGATGCACCTAGTGATTTGGCAATTATTGGACGTTACTTGCTCA
CACCAGAAATTTTTAGTATTTTAGAAAAACAAGAACCTGGTGCAGGCAATGAAGTTCAACTGACTGATGCTATTGATACC
CTCAATAAGACACAGCGTGTCTTTGCTCGTGAGTTTAAAGGGAAACGCTATGATGTTGGCGATAAATTTGGGTTTATGAA
AACTTCTTTGGATTATGCCCTGAAACACCCTCAAGTCAAAGATGACTTGAAAGCCTACATCATCCAACTGGGCAAAGCAC
TAGAGAAGACAAAACCATAA

Protein sequence :
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILIVTGKSKRSIEDHFDSNFELEYNLQA
KGKIELLKLVDETTSINLHFIRQSHPRGLGDAVLQAKTFVGNEPFVVMLGDDLMDITNPNVKPLTKQLIDDYEETHAATI
AVMRVPHEDVSNYGIIAPQAKAVKGLYSVDTFVEKPQPQDAPSDLAIIGRYLLTPEIFSILEKQEPGAGNEVQLTDAIDT
LNKTQRVFAREFKGKRYDVGDKFGFMKTSLDYALKHPQVKDDLKAYIIQLGKALEKTKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 2e-74 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC.2 NP_268587.1 UDP-glucose pyrophosphorylase VFG0964 Protein 2e-133 91