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Name : polA (SPy_0185) Accession : NP_268564.1 Strain : Streptococcus pyogenes SF370 Genome accession: NC_002737 Putative virulence/resistance : Unknown Product : DNA polymerase I Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0749 EC number : 2.7.7.7 Position : 171524 - 174166 bp Length : 2643 bp Strand : + Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair DNA sequence : ATGGAAAACAAGAATAAATTACTATTAATTGATGGGTCATCTGTTGCCTTTCGTGCCTTTTTTGCCCTCTACAATCAAAT TGACCGCTTTAAAAACCATAGCGGTCTTCATACCAATGCCATTTATGGCTTTCATTTGATGCTAGACCACATGATGAAGC GAGTCCAGCCCACACACGTGCTGGTGGCTTTTGATGCGGGCAAAACCACCTTCCGGACAGAAATGTATGCCGATTATAAG GCGGGTCGCGCTAAAACCCCAGAGGAATTTCGTGAGCAGTTTCCTTATATTCGTGAGATGTTGACAGCCCTTGGGATTGC TTATTATGAGTTGGAACACTACGAAGCAGACGATATTATCGGGACGCTTGATAAAATGGCGGAGCGCACAGAAGTGCCTT TTGATGTGACCATTGTCAGTGGTGATAAAGATTTGATCCAGTTAACTGACGAAAATACCGTGGTTGAAATTTCTAAAAAA GGGGTAGCCGAATTTGAAGAATTCACACCGGCTTACCTCATGGAAAAAATGGGATTGACGCCAAACCAGTTTATTGACCT CAAAGCCTTGATGGGAGATAAATCGGATAATATTCCAGGAGTGACCAAAATCGGTGAAAAAACTGGGCTCAAGCTCCTTC ATGAATTTGGTAGTTTAGAAGGTATCTACGAGCATATTGATGGATTCAAGACCTCAAAAATGAAAGAAAACTTGATTAAT GATCGTGACCAAGCTTTCCTATCTAAAACGCTCGCCACTATCAATACAGCATCTCCTATCACAATTGGCTTAGATGATAT TGTCTACAATGGTCCAGATGTTGCTAGTCTCTCTCAATTTTACGATGAGATGGATTTTGTGCAACTCAAGAAAGGTCTTG CTAGCCAGATGCCTCAAGAGCCAGTAGCTGTCATTTCCTATCAAGAAGTGACCAATGTGTCTGCTGATTTGTTTAGCGCA GAAGACATCTTCTACTTTGAAACGCTTCGGGACAATTACCATCGTGAGGCCATCATTGGTTTTGCTTGGGGACATGGTGA GCAGATTTACGCATCCACAGACCTTGGCCTATTAGCGACGGATAGTTTTAAGCAGGTCTTCCAAAAACCCATTGCCACTT ATGATTTTAAACGTAGCAAGGTCTTGTTGAGCCACTTAGGAATTGAGTTGGTAGCACCTAGCTATGATGCTAGATTAGCT AATTACCTTCTGTCAACTGTAGAAGACAATGAGCTTAGCACCATTGCCCGCATTTTTACTGACATCTCTTTGGAAGAAGA CGATACAGTCTATGGTAAAGGTGCTAAACGGGCTGTTCCTGATAAAGACGTCTTACTAGAACACTTAGCTCGTAAGGTCA AAGTATTATTAGATAGCAAGTCTCAAATGCTAGACAAGCTCACTGCCCATGAGCAACTAGACCTCTATCAGAATATTGAA TTGCCTTTGGCTAATGTCCTTGCTAAAATGGAAATTGAAGGGATCAAGGTTAATAGGGCGACTTTGCAAGATATGGCAGA GCAAAACAAGGTCATTATTGAAGCGCTCACCCAAGAGATTTATGATATGGCTGGCCAAGAATTTAATATCAATTCGCCTA AACAGTTAGGCAGTATCTTGTTTGAGAAGATGCAACTACCTCTTGAGATGACTAAGAAGACCAAAACAGGTTATTCTACA GCTGTTAATGTTTTGGAACGTTTGGCACCGATTGCTCCAATTGTGGCTAAAATTTTGGATTACCGCCAGATTACCAAATT ACAGTCTACTTATGTGATTGGTTTACAGGATTATATTCTGGCTGATGGCAAGATTCATACCCGCTATGTGCAGGATCTCA CGCAGACAGGGCGTTTGTCTAGTGTGGACCCTAATCTTCAAAACATTCCCATTCGTTTGGAACAGGGGCGTTTGATTCGT AAGGCCTTTACCCCATCTCATGAAGATGCCGTCTTGTTGAGTTCAGATTACTCACAGATTGAATTGCGGGTACTGGCACA TATTTCAGGGGATGAGCATTTGATTGCTGCCTTTAATGAAGGGGCAGACATTCATACCTCAACGGCTATGCGTGTGTTTG GGATTGACAGGGCAGCAGATGTTACTGCCAATGACCGCCGTAATGCCAAGGCTGTTAACTTTGGAATTGTGTATGGGATT TCTGATTTTGGTTTGTCAAATAACCTTGGTATCACCCGTAAACAGGCCAAGTCTTACATTGATACCTATTTTGAACGCTA TCCTGGGATTAAAGCCTATATGGAAAATGTGGTGCGTGAGGCTAAAGACAAGGGCTATGTAGAGACCCTCTTTAAGCGTC GTCGTGAATTACCGGATATCAACTCTCGTAATTTCAACGTTCGCTCTTTTGCGGAGCGTACAGCCATCAACTCGCCCATT CAAGGAAGCGCAGCTGATATTCTCAAAATCGCTATGATTAATCTGGATAAGGCCTTGCAAGCAGGTGGTTTTAGAGCTAA AATGCTGCTTCAAGTGCATGATGAAATCGTTTTGGAAGTGCCAAATGATGAGTTGACTGCTATAAAAAAACTTGTCAAAG ACACCATGGAAGCTGCTGTTGATTTAGCTGTTCCTTTATGTGTCGATGAAAGTACTGGGCATAGCTGGTACGAAGCCAAA TAA Protein sequence : MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYK AGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKTSKMKENLIN DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAVISYQEVTNVSADLFSA EDIFYFETLRDNYHREAIIGFAWGHGEQIYASTDLGLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIELVAPSYDARLA NYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGAKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYST AVNVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDRAADVTANDRRNAKAVNFGIVYGI SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPI QGSAADILKIAMINLDKALQAGGFRAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGHSWYEAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| polA | YP_281523.1 | DNA polymerase I | Not tested | Not named | Protein | 0.0 | 99 |
