Gene Information

Name : hasC (SPy_2202)
Accession : NP_270109.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Virulence
Product : UDP-glucose pyrophosphorylase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1210
EC number : 2.7.7.9
Position : 1835310 - 1836224 bp
Length : 915 bp
Strand : +
Note : Best Blastp hit = sp|Q54713|HASC_STRPY UTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|995767|gb|AAA91810.1| (U33452) U

DNA sequence : 
ATGACCAAAGTCAGAAAAGCCATTATTCCTGCTGCAGGTCTAGGAACACGTTTTTTACCTGCTACCAAAGCTCTTGCCAA
AGAGATGTTGCCCATCGTTGATAAACCAACCATCCAGTTTATCGTCGAAGAAGCGCTAAAATCTGGCATCGAGGAAATCC
TTGTGGTGACCGGAAAAGCTAAACGCTCTATCGAGGACCATTTTGATTCAAACTTTGAATTAGAATACAACCTCCAAGCT
AAGGGGAAAAATGAACTGTTGAAATTAGTGGATGAAACCACTGCCATTAACCTTCATTTTATCCGTCAAAGCCACCCAAG
AGGGCTGGGAGATGCTGTCTTACAAGCCAAAGCCTTTGTGGGCAATGAACCCTTTGTGGTCATGCTTGGAGATGACTTAA
TGGACATTACAAATGCATCCGCTAAACCTCTCACCAAACAACTCATGGAGGACTATGACAAGACGCATGCATCCACTATC
GCTGTGATGAAAGTTCCTCATGAAGATGTGTCTAGCTATGGGGTTATCGCTCCTCAAGGCAAGGCTGTCAAGGGCCTTTA
CAGTGTAGACACCTTTGTTGAAAAACCACAACCAGAAGATGCGCCTAGTGATTTGGCTATTATTGGTCGTTACCTCCTAA
CCCCTGAAATTTTTGGTATTTTGGAAAGACAGACCCCTGGAGCAGGTAACGAAGTGCAACTCACAGATGCTATCGATACC
CTCAATAAAACTCAGCGTGTCTTTGCACGAGAATTTAAAGGCAATCGTTACGATGTTGGGGATAAATTTGGATTCATGAA
AACATCTATCGACTATGCCTTAGAACACCCACAGGTCAAAGAGGACTTGAAAAATTACATTATCAAACTAGGAAAAGCTT
TGGAAAAAAGTAAAGTACCAACACATTCAAAGTAA

Protein sequence : 
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQA
KGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTI
AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDAIDT
LNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 9e-75 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC NP_270109.1 UDP-glucose pyrophosphorylase VFG0964 Protein 4e-143 100