Gene Information

Name : purA (SPy_0160)
Accession : NP_268541.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 145841 - 147133 bp
Length : 1293 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACATCTGTAGTTGTTGTTGGTACCCAGTGGGGTGACGAAGGTAAAGGTAAAATCACTGATTTCTTGTCAGCGGATGC
AGAAGTAATTGCACGCTATCAAGGTGGTGATAATGCTGGTCATACGATCGTGATTGATGGTAAGAAGTTTAAACTTCACT
TGATCCCATCAGGAATTTTCTTCCCGCAAAAAATTTCCGTTATTGGTAATGGCGTTGTGGTCAACCCCAAATCTTTGGTC
AAAGAGTTGGCGTACCTGCATGATGAAGGAGTGACGACAGATAACCTTCGCATTTCAGACCGAGCTCATGTCATTTTACC
TTATCATATCCAGCTGGATCAACTGCAAGAAGATGCAAAAGGTGACAATAAAATCGGAACAACTATTAAAGGGATTGGTC
CAGCTTATATGGATAAAGCTGCTCGAGTTGGTATCCGTATCGCAGATTTACTGGATAAGGATATCTTTGCAGAGCGCCTA
CGCATTAATTTAGCTGAGAAAAACCGTTTATTTGAAAAAATGTATGACAGTACACCTCTTGATTTTGATGCTATTTTTGA
AGAATACTATGCTTACGGTCAAGAAATCAAGCAATATGTGACAGATACTTCTGTAATTTTAAATGATGCACTTGATGCCG
GTAAACGTGTTCTTTTTGAAGGTGCACAAGGGGTTATGCTTGATATTGACCAAGGAACGTACCCATTTGTAACGTCTTCA
AACCCAGTTGCTGGTGGTGTAACCATTGGTTCTGGTGTTGGCCCAAATAAAATCAACAAAGTAGTTGGTGTCTGTAAAGC
CTACACAAGCCGTGTCGGTGATGGGCCATTCCCTACAGAACTCTTTGATGAAGTGGGTGAGCGCATTCGTGAAGTGGGTC
ATGAGTACGGGACAACGACCGGCCGTCCACGTCGTGTCGGTTGGTTTGATTCGGTTGTCATGCGCCACAGTCGTCGTGTA
TCAGGTATTACTAACCTCTCTCTGAATTCAATTGATGTTCTTTCAGGGCTTGATACGGTTAAGATTTGTGTGGCTTATGA
CCTTGATGGGAAACGTATTGACTATTACCCAGCAAACCTTGAACAACTCAAACGTTGCAAACCAATCTATGAAGAATTAC
CAGGCTGGCAAGAGGACATCACAGGTGTTCGTAGCCTTGATGAGCTTCCTGAAAATGCCCGCAACTACGTTCGTCGTGTT
GGAGAATTGGTTGGCGTTCGCATTTCAACCTTCTCAGTTGGTCCAGGGCGTGAACAGACCAATATTCTTGAGTCAGTCTG
GGCATCTATCTAA

Protein sequence :
MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLV
KELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSS
NPVAGGVTIGSGVGPNKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRV
SGITNLSLNSIDVLSGLDTVKICVAYDLDGKRIDYYPANLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRV
GELVGVRISTFSVGPGREQTNILESVWASI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 0.0 99