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Name : secA (SPy_1805) Accession : NP_269813.1 Strain : Streptococcus pyogenes SF370 Genome accession: NC_002737 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 1496512 - 1499031 bp Length : 2520 bp Strand : - Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCCAATATTCTACGCAAAGTTATCGAAAATGACAAAGGCGAACTAAGAAAATTAGAAAAAATTGCAAAAAAAGTAGA ATCCTACGCAGACCAAATGGCGTCATTGTCGGATAGAGATCTACAAGGAAAAACACTTGAATTTAAAGAACGCTATCAAA AAGGTGAGACCCTCGAACAACTATTACCTGAAGCTTTCGCAGTTGTTCGTGAAGCAGCAAAACGTGTGTTGGGCTTGTTC CCTTATCGTGTTCAAATTATGGGAGGAATTGTTCTTCATAACGGGGATGTCCCTGAAATGCGTACTGGTGAAGGAAAAAC TCTTACAGCCACCATGCCAGTTTATCTCAATGCTATTGCTGGTGAGGGTGTTCACGTTATTACTGTTAATGAGTATCTTT CAACGCGTGACGCTACCGAAATGGGTGAAGTGTATAGCTGGTTAGGTCTTTCAGTTGGGATCAACCTAGCTGCTAAGTCT CCTGCTGAAAAACGTGAAGCTTATAATTGTGATATTACTTATTCAACCAACTCTGAAGTCGGTTTTGATTACCTTCGTGA CAACATGGTTGTTCGCCAGGAAGACATGGTACAACGCCCACTCAATTTTGCCTTGGTTGATGAAGTGGACTCAGTCTTAA TTGACGAGGCAAGGACACCTTTAATTGTTTCTGGTGCTGTTAGCTCTGAAACCAATCAATTGTATATTCGTGCTGACATG TTTGTAAAAACTCTGACGTCAGTGGATTATGTTATTGATGTGCCCACTAAAACGATTGGATTAAGCGATTCAGGTATTGA TAAAGCTGAGAGTTACTTTAACTTGAGCAATCTTTACGATATTGAAAATGTAGCCTTGACTCACTTTATAGACAACGCCC TTCGTGCAAACTATATTATGTTGTTAGATATCGATTATGTGGTCAGCGAAGATGGTGAGATTCTTATTGTTGACCAATTT ACAGGTCGTACGATGGAAGGGCGTCGCTTCTCAGACGGCTTGCACCAAGCTATTGAGGCAAAAGAAGGCGTTCGTATTCA GGAAGAATCAAAAACCAGCGCCTCAATCACTTACCAAAATATGTTTCGTATGTACAAAAAATTGGCAGGTATGACTGGTA CTGCGAAGACCGAGGAAGAAGAATTTCGCGAAGTTTATAACATGCGTATTATTCCAATTCCAACCAATCGTCCAATTGCC CGTATTGATCACACTGATTTGCTTTACCCGACCTTAGAATCAAAGTTTAGAGCAGTTGTGGAAGACGTTAAAACGCGTCA TGCAAAAGGACAACCTATCCTTGTAGGTACGGTTGCTGTTGAAACTAGTGATTTGATTTCACGCAAGCTGGTTGAAGCAG GGATTCCTCATGAGGTTTTGAATGCTAAAAATCACTTTAAAGAAGCTCAAATCATTATGAATGCTGGGCAACGTGGTGCT GTTACAATCGCAACTAACATGGCTGGTCGTGGTACTGATATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGTGGGTTATG TGTCATTGGTACAGAGCGTCATGAAAGCCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG GTGAATCCCAATTCTATCTTTCATTAGAAGATGATTTGATGAGACGTTTCGGCTCTGATCGTATAAAAGCCTTTTTGGAT CGGATGAAATTAGATGAAGAAGACACTGTTATTAAATCAGGTATGTTAGGGCGTCAAGTGGAATCTGCTCAAAAACGGGT TGAAGGAAATAACTATGATACCCGTAAACAGGTCTTACAATATGATGATGTGATGCGTGAACAGCGTGAAATTATCTATG CTAACCGTCGTGATGTCATAACTGCTAATCGAGATCTTGGCCCAGAAATTAAAGCTATGATCAAGCGTACTATCGACCGT GCTGTAGATGCTCATGCACGTAGCAATCGTAAAGATGCTATAGATGCTATTGTAACTTTTGCTAGGACCTCGCTGGTACC AGAAGAGTTTATTAGTGCTAAAGAGTTACGTGGTTTAAAAGATGATCAAATCAAAGAGAAGCTTTATCAAAGAGCGCTTG CTATCTACGACCAGCAACTATCAAAACTTCGTGATCAAGAAGCTATTATTGAATTCCAAAAAGTACTCATTTTGATGATT GTGGATAACAAATGGACTGAACACATTGATGCCTTAGATCAACTTCGTAATGCTGTTGGACTTCGGGGGTATGCTCAAAA TAACCCTGTGGTGGAATACCAAGCAGAAGGTTTCAAGATGTTCCAAGATATGATTGGTGCTATCGAGTTTGATGTAACAC GTACCATGATGAAAGCACAAATTCACGAACAAGAACGTGAACGTGCAAGTCAACGTGCCACAACAGCAGCACCTCAAAAC ATCCAATCGCAGCAGTCAGCTAACACCGATGATTTACCCAAAGTGGAGCGTAACGAAGCTTGTCCATGTGGTTCAGGCAA AAAATTCAAAAATTGTCACGGTCGTAAATCCTTCTCATAA Protein sequence : MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLF PYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM FVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQF TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA RIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLD RMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDR AVDAHARSNRKDAIDAIVTFARTSLVPEEFISAKELRGLKDDQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMI VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQN IQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 6e-144 | 42 |
