Gene Information

Name : nadE (SPy_1652)
Accession : NP_269697.1
Strain : Streptococcus pyogenes SF370
Genome accession: NC_002737
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1371346 - 1372170 bp
Length : 825 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGACACTACAAGAAGAGATAATTCGACAATTAGGCGTCAAGGCTAGCATTGACCCACAAGAAGAAATTCGGAAAGCCGT
TGATTTTTTAAAAGCTTATTTGCGTAAGCACTCATTTTTAAAAACTTATGTCTTAGGCATTTCGGGAGGTCAGGATTCTA
CCCTCGCAGGAAAGCTAGCCCAAATGGCCATTGCAGAGTTACGGGAGGAAGCAAGTGATCAAGCTTACCAATTTATAGCT
GTTCGCTTGCCTTATGGGGTTCAGGCTGATGAAGCAGATGCGCAAAAAGCCTTGGCTTTTATTGCACCAGATCAGACCCT
TACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAGAGGCTCTACAAGCAGCAGGCGTTGAGATTTCTGATTTCAATA
AAGGTAATATTAAAGCACGTCAGCGAATGATCAGTCAATATGCCATTGCTGGCCAAATGGCTGGTGCTGTTATTGGAACG
GATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAAATTTGGTGATGGTGGAGCAGATATTCTTCCCCTCTTTAGGCT
TAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAGGAGCAGATGCTGCTTTGTATGAAAAAGTTCCAACTGCTGATT
TAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCTCTAGGGGTGACCTATCAAGACATCGACGACTATTTGGAAGGG
AAGCTGATTTCCAAAGTAGCTCAAGCAACTATTGAAAAATGGTGGCATAAAGGACAACACAAGCGTCACCTGCCAATCAC
CATTTTTGATGATTTTTGGAAATAA

Protein sequence :
MTLQEEIIRQLGVKASIDPQEEIRKAVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREEASDQAYQFIA
VRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGT
DHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDDYLEG
KLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 8e-62 54