Gene Information

Name : CC_1999 (CC_1999)
Accession : NP_420806.1
Strain : Caulobacter crescentus CB15
Genome accession: NC_002696
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2202451 - 2203899 bp
Length : 1449 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCAAGGCCATCCGCGAAAATCCTAAAGCCTATGACCGCCACTGGTCGGGCAAGGGCCGCTCGGGCGCGGC
TGATGAGGCCGTGCGTCTCGACGCCGAACTGCGCGCGGCTCAGACCACGCTGCAGGAGGCCCAGGCCAAGCGGAACGAAA
GCTCCAAGCTGATCGGCATGGCCAAGGCCAAGAAGGACGAGGCCGAAGCCGCGCGCCTGATGGCCGAGGTCGAGTCGCTC
AAGGGCGTCATGGCCACCGCCGCCGAGGCCGAGAACCTCGCCGACGGCCAGCTGAAGGACCTGCTGGCCAGCCTGCCCAA
TATTCCCGCCCCGGAGGTTCCGGCCGGGGAGGACGAGCATGGCAATCTCGAGCAGCGCCGCTGGGGCGATGCGACCAAGC
TGCCGGCCGGTAAGCTGAACAAGCCCAAGGACCACGTTGACCTGGGCGCTGCCCTGGGCGGCATGGACTTCGAAGCCGCC
GCCCGCATGAGCGGCGCGCGCTTCGTCGTCCTCAAGAAAGAGATCGCCCGCCTGGAGCGCGCCATCGGCCAGTTCATGCT
GGACCTGCAGACGGTCGAGCACGGTTATACGGAGGTCAGCCCTCCGCTGCTGGTAAAGGATCACGCTCTTTATGGAACTG
GGCAACTGCCGAAGTTCGCGGATGACCTATTCGCAACTACGAGCTTTGATCTTGGGCGTTACGACGATGAGTTTGCGCGT
CAAGCGGCTGCTATAGGTTCTGCTCTGGACAAGCTCAGCGATGAGCATCGCAATCAGCTAAAGTATCTGCTTAGCAAAGA
GTACATCCACGCCTCCGTCCAGAATGCTCTAGAGCGTAGTCACTGGCTGATCCCCACCGCCGAAGTCTCCCTCACCAATA
TCGTCCGCGAGCAGCTGGTCGCCGAGGAAGAGCTGCCGATGCGCCTGACGGCGCTGACGCCGTCGTTCCGCGCCGAGGCC
GGTTCTGCCGGTCGCGACACGCGCGGCATGATCCGCCAGCACCAGTTCTATAAGGTCGAGCTGGTCTCGATCACCACGCC
CGACCAGTCGGAAGCCGAGCACCAGCGCATGGTCGAGTGCGCCGAGACGGTGCTGAAGAAGCTGGAGCTGCCGTTCCGCA
CCATGCTGCTGTGCACCGGCGACATGGGCTTTGGCGCGAAGAAGACCTATGACCTGGAGGTCTGGCTGCCGTCGCAGGAC
ATGTACCGCGAGATCAGCTCGTGCTCGAACTGCGGCGACTTCCAGGCGCGGCGCATGGACGCCCGCTATCGCAAGACCGG
CGAAAAGGGCGGCCACTTCGTGCACACCCTGAACGGCTCGGGCCTGGCCGTCGGCCGCACGCTGGTGGCGGTGCTGGAGA
ACTATCAGGACGAGGGCGGTCGCATCCACATCCCGGCGGCGCTGCAGCCCTATATGGGCGGCGTGACGCACATCGGGGGG
CAGGCGTGA

Protein sequence :
MHDIKAIRENPKAYDRHWSGKGRSGAADEAVRLDAELRAAQTTLQEAQAKRNESSKLIGMAKAKKDEAEAARLMAEVESL
KGVMATAAEAENLADGQLKDLLASLPNIPAPEVPAGEDEHGNLEQRRWGDATKLPAGKLNKPKDHVDLGAALGGMDFEAA
ARMSGARFVVLKKEIARLERAIGQFMLDLQTVEHGYTEVSPPLLVKDHALYGTGQLPKFADDLFATTSFDLGRYDDEFAR
QAAAIGSALDKLSDEHRNQLKYLLSKEYIHASVQNALERSHWLIPTAEVSLTNIVREQLVAEEELPMRLTALTPSFRAEA
GSAGRDTRGMIRQHQFYKVELVSITTPDQSEAEHQRMVECAETVLKKLELPFRTMLLCTGDMGFGAKKTYDLEVWLPSQD
MYREISSCSNCGDFQARRMDARYRKTGEKGGHFVHTLNGSGLAVGRTLVAVLENYQDEGGRIHIPAALQPYMGGVTHIGG
QA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-73 45