Gene Information

Name : ECs5275 (ECs5275)
Accession : NP_313302.2
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : protein FimC
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 5399246 - 5399920 bp
Length : 675 bp
Strand : +
Note : periplasmic chaperone required for type 1 fimbriae; similar to FIMC_ECOLI gi|1790771 (conserved in Escherichia coli K-12)

DNA sequence :
TTGCTGGCAGGTATCCTGATGTTCATGGCAATGATGGTTGCCGGACGCGCTGAAGCGGGAGTGGCCTTAGGTGCGACTCG
CATAATTTATCCGGCAGGGCAAAAACAAGTGCAACTTGCCGTGACAAATAATGATGAAAATAGTACCTATTTAATTCAAT
CATGGGTGGAAAATGCCGATGGTGTAAAGGATGGTCGTTTTATCGTGACGCCTCCTCTGTTTGCGATGAAGGGAAAAAAA
GAGAATACCTTACGTATTCTTGATGCAACAAATAACCAATTGCCACAGGACCGGGAAAGTTTATTCTGGATGAACGTTAA
AGCGATTCCGTCAATGGATAAATCAAAATTGACTGAGAATACGCTACAGCTCGCAATTATCAGCCGCATTAAACTGTACT
ATCGTCCGGCTAAATTAGCGTTGCCACCCGATCAGGCCGCAGAAAAATTAAGATTTCGTCGTAGCGCGAATTCTCTGACG
CTGATTAACCCGACACCCTATTACCTGACGGTAACAGAGTTGAATGCCGGAGCCCGGGTTCTTGAAAATGCCTTGGTGCC
TCCAATGGGCGAAAGCACGGTTAAATTGCCTTCTGATGCGGGAAGCAATATTACTTACCGAACAATAAATGATTATGGTG
CACTTACCCCCAAAATGACGGGCGTAATGGAATAA

Protein sequence :
MLAGILMFMAMMVAGRAEAGVALGATRIIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKK
ENTLRILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPPDQAAEKLRFRRSANSLT
LINPTPYYLTVTELNAGARVLENALVPPMGESTVKLPSDAGSNITYRTINDYGALTPKMTGVME

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2C AFH78430.1 putative fimbrial chaperone protein Virulence KpGI-5 Protein 1e-83 84
sfaE CAC16952.2 SfaE protein Virulence PAI III 536 Protein 3e-70 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs5275 NP_313302.2 protein FimC VFG0875 Protein 3e-101 98
ECs5275 NP_313302.2 protein FimC VFG0911 Protein 9e-71 66
ECs5275 NP_313302.2 protein FimC VFG1644 Protein 1e-70 66
ECs5275 NP_313302.2 protein FimC VFG0445 Protein 6e-53 49