Gene Information

Name : ECs4565 (ECs4565)
Accession : NP_312592.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : SepQ
Function : -
COG functional category : N : Cell motility
COG ID : COG1886
EC number : -
Position : 4604025 - 4604942 bp
Length : 918 bp
Strand : -
Note : similar to L0031 [Escherichia coli O157:H7 strain EDL933] gi|3414899|gb|AAC31510.1|, SepQ [Escherichia coli strain E2348/69] gi|2865293|gb|AAC38386.1|; type III secretion system protein

DNA sequence : 
ATGAAGCCATTGAGTTCACAATTGAATATGAAAATTAACGATTTTTATTTGCCGTTGTTGCCAGTTATCGGAACCGGTCG
CCTCTATATTACGTCCAAAGGTCATGCTTGCCATGCATATTTTCGTGAGGTCAGCGGTCATGGTATTCGTTTCACGTTGA
CATACTCGGGCTATGAGGGGCGTTTCTGGATATCAGAAGAACAGTTCATTCAGTGGTGCCAAGAGTTATTCCCGTATAGC
GAAAGCCGGCTGATACCGGAAGATACGATAAAACTCATGATCTTATGGGTAATGCAGACTGCCTTACCGGAAGGTGATGT
GTCAGTTGATGATGTTCAATTTACGATGCTAAATAAAGATATTTATCCGGTAATAGAAAATAATAATGGAGAAAACAGAC
TTAATGTAATTATACTCGAAACAACGGTACAAAGTTTACAATATCTGATTAATGATAATTGGCAATTAGTTCCACATTCT
AATGCTCTTTTTTTTGATGGCTATATCGTACCTGGGTGGACTGATTATCCAGTTACAGAGTTGAGAGTTGGTGATAGTCT
GAGACTCTATCATGTTGATGATAGTCAAGAGAGAAGGTGCTGGATTGTTATTAATACCCCTTTAGCAACAGTAAATCTGA
GTGATAATAATTTATCTGTCACGGATGTTCTGGCTGCGGATCTGTTATCTGCTCTTAGCAATGAGACTGTCATGAATCGC
ATTTATTGTGCGATCGGTACAGTCCATATTGATATACACATGTTGCGTAATGTTAAAAAAGATGACATTATTAATTCAGA
TGGATACCATCTTTTTGGTGGTTGTCAGTTAATACGCAATAATACGACGATAGCATACGGGAGTATTGTAAAAATCAACG
AAGATTTTTATTTTACTGTTAGCATAGTATGTGATTAA

Protein sequence : 
MKPLSSQLNMKINDFYLPLLPVIGTGRLYITSKGHACHAYFREVSGHGIRFTLTYSGYEGRFWISEEQFIQWCQELFPYS
ESRLIPEDTIKLMILWVMQTALPEGDVSVDDVQFTMLNKDIYPVIENNNGENRLNVIILETTVQSLQYLINDNWQLVPHS
NALFFDGYIVPGWTDYPVTELRVGDSLRLYHVDDSQERRCWIVINTPLATVNLSDNNLSVTDVLAADLLSALSNETVMNR
IYCAIGTVHIDIHMLRNVKKDDIINSDGYHLFGGCQLIRNNTTIAYGSIVKINEDFYFTVSIVCD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sepQ AAC31510.1 L0031 Virulence LEE Protein 9e-137 100
sepQ NP_290265.1 hypothetical protein Virulence LEE Protein 1e-136 100
sepQ ACU09455.1 SepQ protein Virulence LEE Protein 9e-137 100
ECs4565 NP_312592.1 SepQ Virulence LEE Protein 1e-136 100
sepQ AAC38386.1 SepQ Virulence LEE Protein 7e-132 94
sepQ YP_003236085.1 T3SS structure protein SepQ Virulence LEE Protein 5e-131 92
sepQ CAI43871.1 SepQ protein Virulence LEE Protein 9e-125 88
sepQ YP_003223472.1 T3SS structure protein SepQ Virulence LEE Protein 1e-124 88
sepQ AAK26718.1 SepQ Virulence LEE Protein 3e-123 87
sepQ AAL57545.1 SepQ Virulence LEE Protein 3e-123 87
sepQ CAC81865.1 SepQ protein Not tested LEE II Protein 1e-124 87
sepQ YP_003232156.1 T3SS structure protein SepQ Virulence LEE Protein 2e-124 87
unnamed AAL06372.1 SepQ Virulence LEE Protein 1e-118 82

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs4565 NP_312592.1 SepQ VFG0809 Protein 5e-137 100
ECs4565 NP_312592.1 SepQ VFG0733 Protein 4e-132 94