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Name : ECs4559 (ECs4559) Accession : NP_312586.1 Strain : Escherichia coli Sakai Genome accession: NC_002695 Putative virulence/resistance : Virulence Product : gamma intimin Function : - COG functional category : N : Cell motility COG ID : COG5492 EC number : - Position : 4596458 - 4599262 bp Length : 2805 bp Strand : - Note : similar to Gamma intimin (L0025) [Escherichia coli strain EDL933] gi|3414893|gb|AAC31504.1| DNA sequence : ATGATTACTCATGGTTGTTATACCCGGACCCGGCACAAGCATAAGCTAAAAAAAACATTGATTATGCTTAGTGCTGGTTT AGGATTGTTTTTTTATGTTAATCAGAATTCATTTGCAAATGGTGAAAATTATTTTAAATTGGGTTCGGATTCAAAACTGT TAACTCATGATAGCTATCAGAATCGCCTTTTTTATACGTTGAAAACTGGTGAAACTGTTGCCGATCTTTCTAAATCGCAA GATATTAATTTATCGACGATTTGGTCGTTGAATAAGCATTTATACAGTTCTGAAAGCGAAATGATGAAGGCCGCGCCTGG TCAGCAGATCATTTTGCCACTCAAAAAACTTCCCTTTGAATACAGTGCACTACCACTTTTAGGTTCGGCACCTCTTGTTG CTGCAGGTGGTGTTGCTGGTCACACGAATAAACTGACTAAAATGTCCCCGGACGTGACCAAAAGCAACATGACCGATGAC AAGGCATTAAATTATGCGGCACAACAGGCGGCGAGTCTCGGTAGCCAGCTTCAGTCGCGATCTCTGAACGGCGATTACGC GAAAGATACCGCTCTTGGTATCGCTGGTAACCAGGCTTCGTCACAGTTGCAGGCCTGGTTACAACATTATGGAACGGCAG AGGTTAATCTGCAGAGTGGTAATAACTTTGACGGTAGTTCACTGGACTTCTTATTACCGTTCTATGATTCCGAAAAAATG CTGGCATTTGGTCAGGTCGGAGCGCGTTACATTGACTCCCGCTTTACGGCAAATTTAGGTGCGGGTCAGCGTTTTTTCCT TCCTGCAAACATGTTGGGCTATAACGTCTTCATTGATCAGGATTTTTCTGGTGATAATACCCGTTTAGGTATTGGTGGCG AATACTGGCGAGACTATTTCAAAAGTAGCGTTAACGGCTATTTCCGCATGAGCGGCTGGCATGAGTCATACAATAAGAAA GACTATGATGAGCGCCCAGCAAATGGCTTCGATATCCGTTTTAATGGCTATCTACCGTCATATCCGGCATTAGGCGCCAA GCTGATATATGAGCAGTATTATGGTGATAATGTTGCTTTGTTTAATTCTGATAAGCTGCAGTCGAATCCTGGTGCGGCGA CCGTTGGTGTAAACTATACTCCGATTCCTCTGGTGACGATGGGGATCGATTACCGTCATGGTACGGGTAATGAAAATGAT CTCCTTTACTCAATGCAGTTCCGTTATCAGTTTGATAAATCGTGGTCTCAGCAAATTGAACCACAGTATGTTAACGAGTT AAGAACATTATCAGGCAGCCGTTACGATCTGGTTCAGCGTAATAACAATATTATTCTGGAGTACAAGAAGCAGGATATTC TTTCTCTGAATATTCCGCATGATATTAATGGTACTGAACACAGTACGCAGAAGATTCAGTTGATCGTTAAGAGCAAATAC GGTCTGGATCGTATCGTCTGGGATGATAGTGCATTACGCAGTCAGGGCGGTCAGATTCAGCATAGCGGAAGCCAAAGCGC ACAAGACTACCAGGCTATTTTGCCTGCTTATGTGCAAGGTGGCAGCAATATTTATAAAGTGACGGCTCGCGCCTATGACC GTAATGGCAATAGCTCTAACAATGTACAGCTTACTATTACCGTTCTGTCGAATGGTCAAGTTGTCGACCAGGTTGGGGTA ACGGACTTTACGGCGGATAAGACTTCGGCTAAAGCGGATAACGCCGATACCATTACTTATACCGCGACGGTGAAAAAGAA TGGGGTAGCTCAGGCTAATGTCCCTGTTTCATTTAATATTGTTTCAGGAACTGCAACTCTTGGGGCAAATAGTGCCAAAA CGGATGCTAACGGTAAGGCAACCGTAACGTTGAAGTCGAGTACGCCAGGACAGGTCGTCGTGTCTGCTAAAACCGCGGAG ATGACTTCAGCACTTAATGCCAGTGCGGTTATATTTTTTGATCAAACCAAGGCCAGCATTACTGAGATTAAGGCTGATAA GACAACTGCAGTAGCAAATGGTAAGGATGCTATTAAATATACTGTAAAAGTTATGAAAAACGGTCAGCCAGTTAATAATC AATCCGTTACATTCTCAACAAACTTTGGGATGTTCAACGGTAAGTCTCAAACGCAAGCAACCACGGGAAATGATGGTCGT GCGACGATAACACTAACTTCCAGTTCCGCCGGTAAAGCGACTGTTAGTGCGACAGTCAGTGATGGGGCTGAGGTTAAAGC GACTGAGGTCACTTTTTTTGATGAACTGAAAATTGACAACAAGGTTGATATTATTGGTAACAATGTCAGAGGCGAGTTGC CTAATATTTGGCTGCAATATGGTCAGTTTAAACTGAAAGCAAGCGGTGGTGATGGTACATATTCATGGTATTCAGAAAAT ACCAGTATCGCGACTGTCGATGCATCAGGGAAAGTCACTTTGAATGGTAAAGGCAGTGTCGTAATTAAAGCCACATCTGG TGATAAGCAAACAGTAAGTTACACTATAAAAGCACCGTCGTATATGATAAAAGTGGATAAGCAAGCCTATTATGCTGATG CTATGTCCATTTGCAAAAATTTATTACCATCCACACAGACGGTATTGTCAGATATTTATGACTCATGGGGGGCTGCAAAT AAATATAGCCATTATAGTTCTATGAACTCAATAACTGCTTGGATTAAACAGACATCTAGTGAGCAGCGTTCTGGAGTATC AAGCACTTATAACCTAATAACACAAAACCCTCTTCCTGGGGTTAATGTTAATACTCCAAATGTCTATGCGGTTTGTGTAG AATAA Protein sequence : MITHGCYTRTRHKHKLKKTLIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHDSYQNRLFYTLKTGETVADLSKSQ DINLSTIWSLNKHLYSSESEMMKAAPGQQIILPLKKLPFEYSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDD KALNYAAQQAASLGSQLQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM LAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKK DYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNEND LLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKY GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSNNVQLTITVLSNGQVVDQVGV TDFTADKTSAKADNADTITYTATVKKNGVAQANVPVSFNIVSGTATLGANSAKTDANGKATVTLKSSTPGQVVVSAKTAE MTSALNASAVIFFDQTKASITEIKADKTTAVANGKDAIKYTVKVMKNGQPVNNQSVTFSTNFGMFNGKSQTQATTGNDGR ATITLTSSSAGKATVSATVSDGAEVKATEVTFFDELKIDNKVDIIGNNVRGELPNIWLQYGQFKLKASGGDGTYSWYSEN TSIATVDASGKVTLNGKGSVVIKATSGDKQTVSYTIKAPSYMIKVDKQAYYADAMSICKNLLPSTQTVLSDIYDSWGAAN KYSHYSSMNSITAWIKQTSSEQRSGVSSTYNLITQNPLPGVNVNTPNVYAVCVE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| eae | NP_290259.1 | intimin adherence protein | Virulence | LEE | Protein | 0.0 | 100 |
| ECs4559 | NP_312586.1 | gamma intimin | Virulence | LEE | Protein | 0.0 | 100 |
| eaeA | AAC31504.1 | L0025 | Virulence | LEE | Protein | 0.0 | 100 |
| unnamed | ACU09449.1 | gamma intimin | Virulence | LEE | Protein | 0.0 | 100 |
| eae | YP_003236079.1 | theta intimin | Not tested | LEE | Protein | 0.0 | 90 |
| eae | CAC81871.1 | Intimin | Not tested | LEE II | Protein | 0.0 | 83 |
| eae | YP_003232162.1 | intimin | Not tested | LEE | Protein | 0.0 | 83 |
| eae | AAK26724.1 | intimin | Virulence | LEE | Protein | 0.0 | 83 |
| eae | AAL57551.1 | Eae | Virulence | LEE | Protein | 0.0 | 83 |
| eae | AAC38392.1 | intimin | Virulence | LEE | Protein | 0.0 | 83 |
| eae | YP_003223466.1 | intimin epsilon | Not tested | LEE | Protein | 0.0 | 82 |
| eae | CAI43865.1 | intimin epsilon | Virulence | LEE | Protein | 0.0 | 82 |
| unnamed | AAL06378.1 | intimin | Virulence | LEE | Protein | 0.0 | 78 |
| eae | AFO66392.1 | intimin-like protein | Virulence | SESS LEE | Protein | 0.0 | 60 |
| eae | AFO66294.1 | intimin-like protein | Not tested | SESS LEE | Protein | 0.0 | 59 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ECs4559 | NP_312586.1 | gamma intimin | VFG0803 | Protein | 0.0 | 100 |
| ECs4559 | NP_312586.1 | gamma intimin | VFG0739 | Protein | 0.0 | 83 |
