Gene Information

Name : ECs4557 (ECs4557)
Accession : NP_312584.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : SepL
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4593776 - 4594831 bp
Length : 1056 bp
Strand : -
Note : similar to SepL (L0023) [Escherichia coli EDL933] gi|3115183|emb|CAA73505.1|, SepL proteins e.g. gi|2865301|gb|AAC38393.1|; type III secretion system protein

DNA sequence :
ATGGCTAATGGTATTGAATTTAATCAAAACCCCGCATCTGTTTTTAATTCTAATTCATTAGATTTTGAATTAGAATCTCA
GCAATTAACGCAAAAAAATTCTTCTAATATTTCTTCGCCATTAATAAATTTGCAAAATGAATTAGCAATGATTACTAGTT
CATCGCTTTCTGAAACGATTGAAGGGCTAAGCCTGGGATATCGCAAAGGTAGCGCAAGGAAAGAAGAGGAAGGCTCGACA
ATCGAGAAGCTGCTCAATGATATGCAAGAGCTGCTTACTCTTACCGATAGTGATAAAATAAAAGAACTATCATTAAAAAA
CAGCGGGCTGCTGGAACAACACGATCCTACTTTGGCGATGTTTGGCAACATGCCAAAGGGGGAAATTGTTGCGCTAATAT
CTTCTTTATTGCAATCTAAGTTTGTTAAGATTGAATTAAAAAAGAAATATGCCAGGTTATTATTAGATTTATTAGGCGAA
GATGATTGGGAGCTGGCTCTGCTTTCCTGGTTAGGGGTGGGTGAGTTAAATCAGGAAGGTATCCAGAAGATCAAGAAGCT
TTATGAAAAGGCTAAGGATGAGGATTCTGAAAATGGCGCCTCTTTACTTGACTGGTTTATGGAGATTAAGGATCTTCCCG
AGCGTGAGAAGCACTTAAAAGTCATTATTAGGGCGCTGTCGTTCGATCTCTCTTATATGTCTTCTTTTGAAGACAAAGTA
AAGACATCTTCAATTATTAGTGATTTATGCAGGGTAATCATTTTTTTATCACTTGATAACTATGCAGATATTATTTCGAT
CTCTATTAAGAAAGATAAAGATATCATTTTAAATGAAGTGTTATCGATTATTGAACATGTCTGGCTAACAGAAGACTGGT
TGCTGGAGAGTCCTTCTCGGGTATCGATTGTCGAAGATAAACATATTTATTATTTTCATTTATTGAAAGACTTTTTTACA
TCATTACCAGATGCTTGCTTTATTGATAGTGAGCAGAGAGAGAATGCATTATTAATGATTGGTAAAGTTATCGACTATAA
GGAGGAAATTATTTGA

Protein sequence :
MANGIEFNQNPASVFNSNSLDFELESQQLTQKNSSNISSPLINLQNELAMITSSSLSETIEGLSLGYRKGSARKEEEGST
IEKLLNDMQELLTLTDSDKIKELSLKNSGLLEQHDPTLAMFGNMPKGEIVALISSLLQSKFVKIELKKKYARLLLDLLGE
DDWELALLSWLGVGELNQEGIQKIKKLYEKAKDEDSENGASLLDWFMEIKDLPEREKHLKVIIRALSFDLSYMSSFEDKV
KTSSIISDLCRVIIFLSLDNYADIISISIKKDKDIILNEVLSIIEHVWLTEDWLLESPSRVSIVEDKHIYYFHLLKDFFT
SLPDACFIDSEQRENALLMIGKVIDYKEEII

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs4557 NP_312584.1 SepL Virulence LEE Protein 6e-133 100
sepL AAC31502.1 L0023 Virulence LEE Protein 4e-133 100
speL ACU09447.1 secretion switching protein SpeL Virulence LEE Protein 4e-133 100
sepL NP_290257.1 hypothetical protein Virulence LEE Protein 6e-133 100
sepL AAC38393.1 SepL Virulence LEE Protein 2e-126 95
sepL AAK26726.1 SepL Virulence LEE Protein 4e-125 95
sepL YP_003232164.1 secretion switching protein SepL Not tested LEE Protein 6e-125 95
sepL AAL57553.1 SepL Virulence LEE Protein 4e-125 95
sepL CAI43863.1 SepL protein Virulence LEE Protein 1e-124 94
sepL CAC81873.1 SepL protein Not tested LEE II Protein 1e-124 94
sepL YP_003223464.1 secretion switching protein SepL Virulence LEE Protein 2e-124 94
sepL YP_003236077.1 secretion switching protein SepL Not tested LEE Protein 2e-124 93
unnamed AAL06380.1 SepL Virulence LEE Protein 1e-119 90
sepL AFO66306.1 putative LEE-encoded type III secretion system component Virulence SESS LEE Protein 1e-92 73
sepL AFO66390.1 putative LEE-encoded type III secretion system component Virulence SESS LEE Protein 1e-92 73

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs4557 NP_312584.1 SepL VFG0801 Protein 2e-133 100
ECs4557 NP_312584.1 SepL VFG0741 Protein 1e-126 95