Gene Information

Name : ECs4556 (ECs4556)
Accession : NP_312583.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : protein EspA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4593139 - 4593717 bp
Length : 579 bp
Strand : -
Note : secreted protein; similar to EspA protein (L0022) [Escherichia coli] gi|3115184|emb|CAA73506.1|, EspA proteins e.g. gi|2388623|gb|AAB71083.1|

DNA sequence : 
ATGGATACATCAAATGCAACATCCGTTGTTAATGTGAGTGCGAGTTCTTCGACATCGACGATCTATGACTTAGGTAATAT
GTCGAAGGATGAGGTGGTTAAGCTATTTGAGGAACTCGGTGTTTTTCAGGCTGCGATTCTCATGTTTTCTTATATGTATC
AGGCACAAAGTAATCTGTCGATTGCAAAGTTTGCTGATATGAATGAGGCATCTAAAGCGTCAACCACGGCACAAAAGATG
GCTAATCTTGTGGATGCCAAAATTGCTGATGTTCAGAGTAGCACTGATAAGAATGCGAAAGCCAAACTTCCTCAAGACGT
GATTGACTATATAAACGATCCACGTAATGACATAAGTGTAACTGGTATTCGTGATCTTAGTGGTGATTTAAGCGCTGGTG
ATCTGCAAACAGTGAAGGCGGCTATTTCAGCTAAAGCGAATAACCTGACAACGGTAGTGAATAATAGCCAGCTCGAAATT
CAGCAAATGTCGAATACATTAAATCTCTTAACGAGTGCACGTTCTGATGTGCAATCTCTACAATATAGAACTATTTCAGC
AATATCCCTTGGTAAATAA

Protein sequence : 
MDTSNATSVVNVSASSSTSTIYDLGNMSKDEVVKLFEELGVFQAAILMFSYMYQAQSNLSIAKFADMNEASKASTTAQKM
ANLVDAKIADVQSSTDKNAKAKLPQDVIDYINDPRNDISVTGIRDLSGDLSAGDLQTVKAAISAKANNLTTVVNNSQLEI
QQMSNTLNLLTSARSDVQSLQYRTISAISLGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
espA AAC31501.1 L0022 Virulence LEE Protein 2e-74 100
espA ACU09446.1 secreted protein EspA Virulence LEE Protein 2e-74 100
espA NP_290256.1 hypothetical protein Virulence LEE Protein 3e-74 100
ECs4556 NP_312583.1 protein EspA Virulence LEE Protein 3e-74 100
espA YP_003232165.1 translocator EspA Virulence LEE Protein 7e-69 86
espA AAK26727.1 EspA Virulence LEE Protein 5e-69 86
espA AAL57554.1 EspA Virulence LEE Protein 5e-69 86
espA CAC81874.1 EspA protein Virulence LEE II Protein 5e-69 86
espA YP_003236076.1 translocon EspA Virulence LEE Protein 1e-65 85
espA AAC38394.1 EspA Virulence LEE Protein 2e-66 85
espA YP_003223463.1 translocon EspA Virulence LEE Protein 7e-68 82
espA CAI43862.1 EspA protein Virulence LEE Protein 5e-68 82
espA AAO66617.1 EspA beta variant Virulence LEE Protein 3e-66 82
unnamed AAL06381.1 EspA Virulence LEE Protein 2e-64 80
espA AFO66389.1 putative secreted protein EspA Virulence SESS LEE Protein 6e-62 79
espA AFO66319.1 putative secreted protein EspA Not tested SESS LEE Protein 6e-62 79

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs4556 NP_312583.1 protein EspA VFG0800 Protein 9e-75 100
ECs4556 NP_312583.1 protein EspA VFG0742 Protein 7e-67 85