Gene Information

Name : ECs3850 (ECs3850)
Accession : NP_311877.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : virulence-related membrane protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3637
EC number : -
Position : 3857829 - 3858377 bp
Length : 549 bp
Strand : -
Note : similar to virulence-related membrane proteins e.g. pagC [Salmonella typhimurium] gi|129558|sp|P23988|PAGC_SALTY

DNA sequence :
ATGATATTATATGTTATGAGTGGTTCAAGACTGGCTGATAATCATACGCTATCGGCTGGTTATGCTCAGAGTAAGGTACA
GGACTTTAAGAATATTAAAGGAGTGAATCTGCAATATCGATATGAGTGGGATTCTCCGGTCAGTGTCGTCGGGAGTTTTT
CGTATATGAAAGGTGATTGGGCGGACAGTCATCGCGATGAAGCTGACGATTTTTACAGACATCAGGCTGATATTAAATAT
TATTCATTTCTCGCAGGCCCAGCTTATCGTCTGAATGACTATATCAGTTTTTATGGTTTGGTGGGGATATCTCATACTAA
AGCGAAGGGAGATTATGAGTGGAGAAACAGTGTGGGTGCTGATGAGTCTGATGGATATTTAAGTGAGTCTGTATCAAAAA
AATCCACTGATTTTGCTTATGCAGCTGGTGTTATTATTAATCCGTGGGGCAATATGTCTGTAAATGTTGGGTATGAGGGA
ACTAAAGCAGATATATATGGAAAACATTCGGTCAATGGATTTACTGTTGGAGTTGGTTATCGTTTTTAA

Protein sequence :
MILYVMSGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHRDEADDFYRHQADIKY
YSFLAGPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEG
TKADIYGKHSVNGFTVGVGYRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pagC AGI37340.1 PagC Virulence OI-122 Protein 4e-63 100
pagC AGI37347.1 PagC Virulence OI-122 Protein 4e-63 100
Z4321 NP_289546.1 PagC-like membrane protein Not tested OI-122 Protein 5e-76 100
pagC AGI37341.1 PagC Virulence OI-122 Protein 8e-62 99
pagC AGI37349.1 PagC Virulence OI-122 Protein 8e-62 99
Z4321 AAQ19134.1 putative PagC-like membrane protein Not tested PAI I CL3 Protein 6e-75 99
pagC AGI37352.1 PagC Virulence OI-122 Protein 8e-62 99
unnamed ADD91732.1 putative PagC-like membrane protein Not tested PAI-I AL862 Protein 3e-77 99
ECO103_3556 YP_003223422.1 PagC-like membrane protein Not tested LEE Protein 4e-56 99
pagC AGI37337.1 PagC Virulence OI-122 Protein 7e-62 98
pagC AGI37342.1 PagC Virulence OI-122 Protein 7e-62 98
pagC AGI37344.1 PagC Virulence OI-122 Protein 7e-62 98
pagC AGI37346.1 PagC Virulence OI-122 Protein 7e-62 98
pagC AGI37343.1 PagC Virulence OI-122 Protein 1e-61 98
pagC AGI37350.1 PagC Virulence OI-122 Protein 7e-62 98
pagC AGI37353.1 PagC Virulence OI-122 Protein 1e-61 98
pagC AGI37348.1 PagC Virulence OI-122 Protein 2e-61 97
pagC AGI37351.1 PagC Virulence OI-122 Protein 2e-61 96
pagC YP_216243.1 PhoP regulated protein: reduced macrophage survival Not tested SPI-11 Protein 6e-28 47