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Name : ECs3731 (ECs3731) Accession : NP_311758.1 Strain : Escherichia coli Sakai Genome accession: NC_002695 Putative virulence/resistance : Virulence Product : EivA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG4789 EC number : - Position : 3729231 - 3731291 bp Length : 2061 bp Strand : - Note : similar to type III secretion proteins e.g. InvA [Salmonella typhimurium] gi|476819|pir||A42888 DNA sequence : ATGTTTAACAAAGTTTTGGTAGGGTTAAGGAGTCATCCAGAATTAATAATTCTTGGATTAATGGTGATGATTATCGCCAT GCTCATAATTCCATTGCCCACCTATTTAATCGACTTTTTGATTGGGCTTAACTTAACATTGGCAATACTTGTATTTTTAG GATCATTCTATGTTGATAGGATCTTAAGCTTTTCTTCATTTCCATCAATCCTCCTTATCACAACGTTATTTCGTTTGGCG CTGGCGATCAGTACCAGTCGACTTATACTTCTTGAGGCGGATGCTGGAGAAATTATAACGAGTTTTGGTGAGTTCGTTAT TGGAGATAGCCTGGTAGTTGGTTTTGTTATTTTCTCCATTGTTACTATTGTTCAGTTTATCGTGATTACTAAAGGTTCGG AACGTGTGGCTGAAGTTGCTGCCCGCTTTTCGCTTGACGGTATGCCAGGTAAACAAATGAGCATTGACGCCGATCTACGC GCCGGGATCATTGATGCAGATTTAGCAAAAGAACGTCGTAGTGTATTAGAACGAGAGAGCCAGTTGTATGGTTCCTTTGA TGGTGCGATGAAATTTATCAAAGGTGATGCTATTGCAAACATTATTATTATCTTTGTTAATATTATCGGTGGGCTATCAG TAGGAGTAGGCCAAAATGGAATGGATTTCTCAACAGCGTTGACTGTCTACACAATTCTTACTGTCGGTGATGGTCTTGTT TCTCAAATTCCAGCTTTATTAATTGCTATTAGCGCAGGATTTATCGTTACGCGCGTAAATGGCGATAGTGATAATATGGG GCAAAATATAATGTCCCAGTTATTAAGTAATTCTTTTGTCATTGTTGTGACATGTGTCCTCGCGCTAAGTATTGGGTTGC TTCCAGGTTTTCCCCTTCTAGTGTTTTTATGTTTGGCAGTAATCTTAGGAATTTACTTTTACTTTAAATTCAAAAAGAAA GGGACTGAAGAAACGGTTGTTGAGGGAGATATTACCGTTGGGTTGGAACCCTATAATCAAGATGATGATATCTCATTAGG TATCATTAATAAACTTGATCAGGTTATTACCGAAACGGTACCCTTGGTCTTGATTATGAATAGTGTACAGGCTAAAAAAT ACACTGAAATCAATCTTGCTGATAGGATTCGTAGTCAGTTTTTTATTGAGTATGGTATCCGCATTCCCGGTATTGTCATT CGTGAGGGGGAAGGTCTTAATGATGAAGATGTCATATTAATGCTAAATGAAGTCAGAGCTTCACAATTTAAAATTTATCA TGATCTTGTCTTGTTGGTTGAATATTCAGATGAAGTGGTTTCGACTTTGATCAAGAAACCTGTCATTGTAAATAGTAATG GTGAACAATATTATTGGGTTACGAAAAGTGATGCTCAAAAATTAACAAAAATTGGCTGTTATACTCGCACGGCCATGGAT GAAATGTATAATCATTTATCTGTCTGTCTGGCTCATAATATTAATGAGTACTTTGGTATACAAGAAACAAAATATATTCT TGATCAATTAGAGATGAAGTATTCTGATCTATTAAAAGAAATATTAAGATATATAACCGTGCAGCGCATTTCAGAGGTAA TTCAGCGTCTGATCCAGGAGCGAATTTCAGTGCGCAATATGCGGTTAGTTATGGAGGCCTTAGCATTATGGAGCCCACGA GAGAAAGATATAATCACACTCGTCGAGCATGTACGAGGTGCATTAGGTCGCTACATTTGCCATAAGTTTTCATATTCTGG AGAAATTAAAGCAATTGTGATTTCGCCTGAAATAGAGGACAGAATCAGAGATGGTGTCAGGCCTACCGCTGGCGGTACTT TTCTTAATCTCGATGCATCCGAAGCTGAGATGATTCTGGATAATTTTAAACTGGCACTTTCTGGAATCAATATTCCTATT AAAGACATTATTTTACTGGGATCTGTGGATATTCGTCGTTTTATCAAAAAACTTATTGAATCTAGTTATCGAGACCTCGA AGTACTTTCGTACGGGGAACTAACGGAAAATGTTCCCGTTAATATTCTGAAAACTATTTAG Protein sequence : MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ECs3731 | NP_311758.1 | EivA | Not tested | LIM | Protein | 0.0 | 100 |
| invA | YP_217815.1 | invasion protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | NP_457290.1 | possible secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | NP_806499.1 | virulence-associated secretory protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | NP_461817.1 | needle complex export protein | Virulence | SPI-1 | Protein | 0.0 | 65 |
| invA | AAS66860.1 | InvA | Not tested | SSR-2 | Protein | 6e-155 | 56 |
| ysaV | AAS66840.1 | YsaV | Not tested | SSR-1 | Protein | 1e-150 | 55 |
| escV | AAC38382.1 | EscV | Virulence | LEE | Protein | 4e-89 | 41 |
| escV | AAC31514.1 | L0035 | Virulence | LEE | Protein | 3e-89 | 41 |
| escV | NP_290269.1 | hypothetical protein | Virulence | LEE | Protein | 5e-89 | 41 |
| escV | ACU09459.1 | EscV protein | Virulence | LEE | Protein | 3e-89 | 41 |
| ECs4569 | NP_312596.1 | hypothetical protein | Virulence | LEE | Protein | 5e-89 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ECs3731 | NP_311758.1 | EivA | VFG0557 | Protein | 0.0 | 65 |
| ECs3731 | NP_311758.1 | EivA | VFG1006 | Protein | 1e-171 | 61 |
| ECs3731 | NP_311758.1 | EivA | VFG0064 | Protein | 4e-102 | 42 |
| ECs3731 | NP_311758.1 | EivA | VFG0729 | Protein | 2e-89 | 41 |
| ECs3731 | NP_311758.1 | EivA | VFG0813 | Protein | 2e-89 | 41 |
