Gene Information

Name : ECs3716 (ECs3716)
Accession : NP_311743.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Virulence
Product : EprK
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4669
EC number : -
Position : 3719204 - 3719938 bp
Length : 735 bp
Strand : -
Note : lipoprotein precursor (type III secretion system); similar to lipoprotein precursors in type III secretion system e.g. PrgK protein [Salmonella typhimurium] gi|1172615|sp|P41786|PRGK_SALTY; type III secretion system lipoprotein precursor

DNA sequence :
ATGAAATATATATCATTATTATTGTTTATCCTGCTGTTGTGCGGCTGCAAGCAGCAGGAATTACTGAACCATCTTGATCA
ACAGCAAGCTAATGATGTCCTTGCTGTTTTACAAAGACATAATATTAATGCTGAAAAGAAGGATCAAGGCAAAACTGGAT
TCTCAATCTATGTTGAACCAACGGATTTTGCTTCTGCGGTGGATTGGCTAAAAATCTACAATCTCCCGGGTAAGCCTGAT
ATTCAAATATCGCAGATGTTCCCTGCAGATGCACTCGTTTCATCTCCACGAGCGGAAAAAGCAAGGCTATATTCTGCTAT
TGAGCAGCGGTTAGAGCAATCTCTCAAAATTATGGATGGTATTGTTTCTTCGAGAGTACATGTTAGTTACGATGTTGATA
CTGGCGATAGTGGTAAAACTGCTTTACCAATTCATATTTCTGTACTTGCAGTATATGAAAAAGATATCAATCCAGAAATA
AAAATAAATGACATAAAGAGATTTATTGTTAATAGTTTTGCAAGCGTACAATATGAGAATATTTCTGTTGTATTGTCAAA
ACGAAGAGACATTATTGAGCAAGCACCAACATATGAAATTAGCGAACCTGTTTTTGCTTATGATAAGGCTATGCCGGTTT
CTATCTTACTTGCATTAATATCCGTAGCGACTTGCTGGCTGTTATGGAAGTATAGGGCCATTCTAACTAATTTAGTCAGG
TTGAAAATTAAGTAG

Protein sequence :
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIVSSRVHVSYDVDTGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSFASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3716 NP_311743.1 EprK Not tested LIM Protein 1e-106 100
eprK AAZ31284.1 EprK Virulence ETT2 Protein 4e-105 99
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 6e-55 56
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 3e-54 56
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 3e-54 56
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 6e-55 56
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 6e-52 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs3716 NP_311743.1 EprK VFG0533 Protein 1e-54 56
ECs3716 NP_311743.1 EprK VFG0998 Protein 8e-44 45
ECs3716 NP_311743.1 EprK VFG1787 Protein 1e-37 43