Gene Information

Name : ECs0289 (ECs0289)
Accession : NP_308316.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 310806 - 311987 bp
Length : 1182 bp
Strand : +
Note : similar to integrases e.g. [phage phi-R73] gi|93827|pir||A42465

DNA sequence : 
ATGCCTTTAAACGATATGCAGATTCGCCGCGCTAAGCCTGAAGCTAAAGCCTATACATTTGGAGATGGGCTAGGGTTGTC
ATTACTTATAGAACCTAATGGAAGCAAGAGTTGGCGGTTCCGCTATCGCTATGCCGGCAAACCCAAAATGATCTCGCTTG
GTGTTTACCCAACGATCACCCTTGCCGATGCTCGTTCCCGTCGTGATGAAGCTCGAAAACTTGTGGCAGAAGGAAAGAAC
CCTAGTGAGGTTCGAAAAGAGCAAAAGCTAGCTATGCAAACAGAGTCAGAGAACGCCTTCGAAAAGATAGCCAGAGAGTG
GCATCAACTTAAATCTGCTAAATGGTCGGCGGGATATGCATCAGACATCATGGAAGCGTTTAAGAACGACATTTTTCCTT
ATGTCGGAACAAGGCCTGTGGGAGAGATTAAACCGCTAGAGCTGCTGAACGTTCTGCGTAAAATTGAGAAACGTGGTGCG
TTGGAGAAAATGCGCAAAGTGCGGCAGCGTTGCTCCGAAGTGTTTCGCTACGCAATTGCAACGGGTAGGGCGGAGTACAA
TCCTGCGGCTGATCTCTCCAGCGCTCTCGAAGTACACCAATCCAATCATTTCCCATTCCTAAAAGCTGATGAGATACCTG
ATTTTCTACGTGCCTTAGAGGGTTACTCCGGGAGTAAGCTTGTCCAGATAGCCACGAAATTACTGATGATTACGGGTGTG
AGAACCATCGAATTACGCGCGGCATTATGGCAAGAATTTGATCTGGATAACGCTATTTGGGAAATTCCTGCTGAAAGGAT
GAAAATGCGTAGGCCACATCTTGTGCCCTTATCATCTCAAGCGGTAGATTTACTCAATGAACTCAAGATCATGACAGGGA
ACTATCGTTATGTTTTTCCAGGGCGGAACGATCCGAATAGGCCAATGAGCGAAGCGAGTATAAATCAAGCCATTAAGCGT
ATTGGGTATGGAGGAAAAGTCACTGGACATGGTTTTCGTCATACCCTTTCTACAATCCTGCATGAGCAAGGTTTTGAGAG
TGCTTGGATTGAAATCCAGTTGGCTCATGTAGATAAAAATTCTATTAGGGGGACTTATAACCATGCTCAATATTTTAGTG
GAAGGAAGTCTATGATGGACTGGTACAGTAATTTGATATTTGAAAGACTAAAAAGGAGTTAA

Protein sequence : 
MPLNDMQIRRAKPEAKAYTFGDGLGLSLLIEPNGSKSWRFRYRYAGKPKMISLGVYPTITLADARSRRDEARKLVAEGKN
PSEVRKEQKLAMQTESENAFEKIAREWHQLKSAKWSAGYASDIMEAFKNDIFPYVGTRPVGEIKPLELLNVLRKIEKRGA
LEKMRKVRQRCSEVFRYAIATGRAEYNPAADLSSALEVHQSNHFPFLKADEIPDFLRALEGYSGSKLVQIATKLLMITGV
RTIELRAALWQEFDLDNAIWEIPAERMKMRRPHLVPLSSQAVDLLNELKIMTGNYRYVFPGRNDPNRPMSEASINQAIKR
IGYGGKVTGHGFRHTLSTILHEQGFESAWIEIQLAHVDKNSIRGTYNHAQYFSGRKSMMDWYSNLIFERLKRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 6e-125 64
int AAC31482.1 CP4-like integrase Not tested LEE Protein 4e-125 61
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 5e-125 61
int ACU09430.1 integrase Not tested LEE Protein 4e-125 61
ECs4534 NP_312561.1 integrase Not tested LEE Protein 5e-125 61
int AAD44730.1 Int Not tested SHI-2 Protein 4e-125 61
aec33 AAW51716.1 Int Not tested AGI-3 Protein 4e-125 61
int CAC39282.1 integrase Not tested LPA Protein 7e-125 61
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-124 61
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 3e-124 61
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 3e-124 61
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-121 59
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 4e-75 42
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 4e-75 42
BJAB0715_01002 YP_008216150.1 Integrase Not tested AbaR27 Protein 6e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECs0289 NP_308316.1 integrase VFG0783 Protein 2e-125 61
ECs0289 NP_308316.1 integrase VFG0598 Protein 1e-124 61