Gene Information

Name : dadX (ECs1685)
Accession : NP_309712.1
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 1680399 - 1681388 bp
Length : 990 bp
Strand : +
Note : catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA

DNA sequence :
ATGACCCGTCCGATACAGGCCAGCCTCGATCTGCAGGCATTAAAACAGAATCTGTCCATTGTCCGCCAGGCCGCGCCGCA
CGCGCGCGTCTGGTCGGTGGTAAAAGCGAACGCTTACGGGCACGGTATTGAGCGTATCTGGAGCGCGCTCGGGGCTACCG
ATGGCTTTGCATTACTTAACCTGGAAGAAGCAATAACGTTACGTGAGCGCGGCTGGAAAGGACCGATCCTGATGCTGGAA
GGATTTTTCCATGCTCAGGATCTGGAAATGTATGACCAGCACCGCCTGACCACCTGCGTACACAGCAACTGGCAGCTCAA
AGCACTGCAAAATGCGCGGCTAAAAGCACCGTTGGATATTTATCTTAAAGTGAACAGTGGGATGAATCGGTTGGGCTTCC
AGCCCGATCGCGTGCTTACCGTCTGGCAGCAGTTGCGGGCGATGGCGAATGTTGGCGAAATGACCCTGATGTCGCATTTT
GCCGAGGCGGAACATCCTGATGGAATTTCCGGCGCGATGGCGCGTATTGAGCAGGCGGCGGAAGGGCTGGAGTGTCGGCG
TTCGTTGTCCAATTCGGCGGCGACTCTGTGGCACCCAGAAGCGCATTTTGACTGGGTTCGGCCTGGCATTATTTTGTATG
GCGCTTCGCCGTCCGGTCAGTGGCGTGATATCGCCAATACTGGATTACGTCCGGTGATGACGCTAAGCAGTGAGATTATT
GGTGTCCAGACGCTAAAAGCGGGCGAGCGTGTGGGCTACGGCGGTCGTTATACTGCGCGCGATGAGCAGCGAATCGGCAT
TGTTGCCGCAGGATACGCCGACGGTTATCCGCGCCACGCGCCTACCGGTACCCCTGTTTTAGTGGACGGCGTGCGCACCA
TGACGGTGGGGACAGTCTCGATGGATATGCTGGCGGTCGATTTAACGCCTTGCCCGCAGCGGGATATTGGTACGCCAGTT
GGAGCTGTGGGGCAAGGAGATCAAAATTGA

Protein sequence :
MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIERIWSALGATDGFALLNLEEAITLRERGWKGPILMLE
GFFHAQDLEMYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII
GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQRDIGTPV
GAVGQGDQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 3e-146 98