Gene Information

Name : lolD (ECs1495)
Accession : NP_309522.2
Strain : Escherichia coli Sakai
Genome accession: NC_002695
Putative virulence/resistance : Resistance
Product : lipoprotein transporter ATP-binding protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 1535744 - 1536445 bp
Length : 702 bp
Strand : +
Note : outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone

DNA sequence : 
ATGAATAAGATCCTGTTGCAATGCGACAACCTGTGCAAACGCTATCAGGAAGGCAGTGTGCAAACCGATGTACTGCACAA
TGTCAGTTTCAGCGTGGGCGAAGGTGAAATGATGGCGATCGTCGGTAGCTCTGGTTCCGGTAAAAGTACCTTGCTGCACC
TGCTGGGCGGGCTGGATACACCAACCTCCGGCGATGTGATCTTTAACGGTCAACCGATGAGCAAACTGTCTTCGGCGGCG
AAAGCAGAACTGCGCAACCAGAAGCTGGGCTTTATTTATCAGTTTCACCACCTGCTGCCGGATTTTACTGCCCTGGAAAA
CGTGGCTATGCCGCTGCTGATTGGCAAGAAAAAGCCCGCTGAAATCAACAGCCGTGCACTTGAGATGTTAAAAGCGGTGG
GGCTGGAGCATCGTGCGAATCACCGCCCATCTGAACTTTCTGGCGGCGAACGCCAGCGTGTGGCGATTGCCCGTGCGCTG
GTCAATAACCCGTGGCTGGTACTGGCGGATGAACCTACCGGTAACCTCGATGCGCGTAACGCAGACAGCATCTTCCAGTT
GCTTGGGGAATTGAATCGCTTGCAGGGCACCGCCTTCCTGGTGGTTACTCACGACCTGCAACTGGCGAAACGTATGAGCC
GCCAACTGGAGATGCGTGATGGTCGTCTGACGGCGGAACTGAGCCTGATGGGGGCGGAGTAA

Protein sequence : 
MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAA
KAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
VNNPWLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-27 42
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 4e-28 41
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 4e-28 41
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 4e-28 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lolD NP_309522.2 lipoprotein transporter ATP-binding protein NC_008702.1.4606598. Protein 3e-37 49
lolD NP_309522.2 lipoprotein transporter ATP-binding protein NC_012469.1.7686878. Protein 3e-41 45
lolD NP_309522.2 lipoprotein transporter ATP-binding protein CP001581.1.gene798.p Protein 5e-37 41