Gene Information

Name : TVN0099 (TVN0099)
Accession : NP_110618.1
Strain : Thermoplasma volcanium GSS1
Genome accession: NC_002689
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 102621 - 103931 bp
Length : 1311 bp
Strand : -
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGTACGACGCAGTTGTACTTGGGGCTGGGCCAGGTGGATACGCTGCGGCCATTAGGCTTGGCCAAAGAAAAAAGAAGGT
AGCCATAATAGAGAAGGACAAGATAGGAGGCGAGTGCCTAAACTATGGCTGCATACCATCTAAGGCGATCATCGAGCTTG
CTAATTCAATAAATTACCTAAAGGAGATGCCCGGAGTATCGATTAATTACAATGTAGACATGAAAAAATGGCAGGAATGG
AAATGGTCCATGATTAACAAGCTTACAGGTGGCGTTGAACTTCTCCTTAAGGCGTATGGCGTTGACATCTTCAGAGGCAC
AGGATACATACAAGACAAGAACCACGTGAAAGTCAACGATAAGGTTCTTGAGACAGATAGCCTTGTCATAGCTACTGGTT
CTAAGCCTGTTTCAATCAACGGGATAAATGATGTGATGTATAACCGCGAAGTCTTAGATCTCGACCATATACCCTCTTCG
ATTGTTATAATTGGCGGAGGATACATCGGTGTTGAAATAGGAATAGCTCTAGCTAAGCTCGGAAGCAAGGTGACCATAGT
TGAGATGATGCCATCAATACTGCCTGGTACGGATAATGAGCTAGTAAGGCACGTAGTAAGGAGGATGTCGCAGTTAGGCA
TAAACGTAATAACAGGGAGAAAGGTTTTATCTACTGCGAAAAACGGGGAAGTCACTGTTAAATTAGATGATGGACAAGAA
CTACGCGCCGAAAAGGTGCTCATGACTGTTGGGAGGATCCCAAATACTGAAGGATTCGGACTGGAGAATCTGAAGCTAGC
CATGGATGGCCGCTTCATAAAGACCGATTCCAGGAAGATGACGAGTGTGAAAGGAGTTTACGCGATAGGTGATGTTTCAG
GACAGCCTATGCTTGCACACAAGGCATACTATGAGGCAGATATCGCTGCGGACAATATATGCGGCATAGATAGCGAAGTT
GATTACAGGGCCATGCCCTACGTTATATATTCAGATCCGGAAATAGCCTATACTGGCGTGAAGGGAGCAAAGTCCACAAG
GTTTCCTGTCGCTGCAAACGGTAGGTCACTAACAATGAATGAAAACATAGGCACCTTCAACATATACTATGATGAAAAAG
GCATAGTGACGGGCGCAGGAATCGCAGCACCTCATGCGAGCGAGCTAATCTCAGAGATATCGCTTGCCGTTGAATCAGGG
CTAATGGCAATGGATATAGGTTTAACTATACACCCGCATCCGACCGTTTCAGAAGGCGTTAAGGAGAGCGCAGAAGAGGT
TTACGGTAAGCCATTGCACTTCAAATTATGA

Protein sequence :
MYDAVVLGAGPGGYAAAIRLGQRKKKVAIIEKDKIGGECLNYGCIPSKAIIELANSINYLKEMPGVSINYNVDMKKWQEW
KWSMINKLTGGVELLLKAYGVDIFRGTGYIQDKNHVKVNDKVLETDSLVIATGSKPVSINGINDVMYNREVLDLDHIPSS
IVIIGGGYIGVEIGIALAKLGSKVTIVEMMPSILPGTDNELVRHVVRRMSQLGINVITGRKVLSTAKNGEVTVKLDDGQE
LRAEKVLMTVGRIPNTEGFGLENLKLAMDGRFIKTDSRKMTSVKGVYAIGDVSGQPMLAHKAYYEADIAADNICGIDSEV
DYRAMPYVIYSDPEIAYTGVKGAKSTRFPVAANGRSLTMNENIGTFNIYYDEKGIVTGAGIAAPHASELISEISLAVESG
LMAMDIGLTIHPHPTVSEGVKESAEEVYGKPLHFKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 6e-65 41