Gene Information

Name : mlr5497 (mlr5497)
Accession : NP_106153.1
Strain : Mesorhizobium loti MAFF303099
Genome accession: NC_002678
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 4410608 - 4411336 bp
Length : 729 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGTCCACCTTGATCTTGATACCGGCCCGCATGGCCTCCACCCGCCTGCCGGGCAAGCCGCTGGCCGACATATCCGGCGC
GCCGATGATCGTCCATGTCGCCCGCCGCGCGGCCGAAGCCGGCCTCGGGCGGGTGGTGGTGGCGACCGACACGCAAAGCG
TCGCCGAAGCGGTGCGCGCGCATGGTTTCGAGGCGGTGATGACGCGCATCGACCACGAATCCGGCTCCGACCGCATCCAC
GAGGCGCTGGCCGCGCTTGATCCCGGGCGCAAGGTCGAAACCATCGTCAATGTGCAGGGCGACCTGCCGACCATCGATCC
CGGCATCATCGCCGCCTCGCTCAGGCCGTTCGAGGACGCGGCGGTGGATATCGCCACGCTCGGCGTCGAGATCGTCCGCG
AAGAGGAAAAGACCAACCCGAACGTCGTCAAGATCGTCGGTTCGCCGCTGTCAGCCACGCGGCTGAGGGCGCTCTATTTC
ACCCGCGCCACAGCACCTTGGGGCGAGGGGCCGCTCTATCACCATGTCGGTCTCTACGCCTATCGCCGCTCGGCACTCGA
ACGCTTCGTCGCGCTGAAACCGTCGCCGCTCGAGCGCCGCGAGCGGCTGGAGCAGTTGCGGGCGCTGGAAGCCGGCATGC
GCATCGATGCCGAGATCGTCCGGTCGCTGCCGCTTGGCGTCGACACGCCGCAAGACCTTGAGCGCGCCCGAACCATTCTT
TCCAACTGA

Protein sequence :
MSTLILIPARMASTRLPGKPLADISGAPMIVHVARRAAEAGLGRVVVATDTQSVAEAVRAHGFEAVMTRIDHESGSDRIH
EALAALDPGRKVETIVNVQGDLPTIDPGIIAASLRPFEDAAVDIATLGVEIVREEEKTNPNVVKIVGSPLSATRLRALYF
TRATAPWGEGPLYHHVGLYAYRRSALERFVALKPSPLERRERLEQLRALEAGMRIDAEIVRSLPLGVDTPQDLERARTIL
SN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-27 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-27 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-27 44