Gene Information

Name : cvrA; nhaP2; ycgO (mlr3752)
Accession : NP_104789.1
Strain : Mesorhizobium loti MAFF303099
Genome accession: NC_002678
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 3019839 - 3021722 bp
Length : 1884 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGGAGCATGCGATCTATCTCGTTACGCTGGTCGGCACGGCGCTCGTTGTCGCCGCCGCGTTTTCGAGCCTGATCGCCTT
CCGCTTCGGTGCCCCCCTCCTGCTGCTCTTTCTCTGCATCGGGCTCGCCACCGGAACCGATGGCCTCGGCATAGAATTCG
ACAATGCCCGCATCGCCTATTTTGCCGGCTCACTGGCTCTCGCCGTCATCCTGTTCGATTCCGGCTTCGGCACGCCGCTC
AACGCCTTGCGGCAGGCGGCCGGCCCGGCGCTGTCGCTGGCGACCTTCGGCGTGCTTCTCACCACCGGCCTGTTCGGCGC
CGCGGCCTACTATCTGCTTGACCTCACCTGGCTGGAATCCTTCCTGCTCGGCGCCGCCGTCGCTTCGACCGACGCCGCGG
CGGTGTTCTTCCTGCTGCGCGCCGGCGAGATCAATCTGCGTGAGCGTGTGCGCTCGACGCTCGAGGTGGAATCCGGCACC
AACGACCCGATCGCCATCTTCCTGACCATCACCCTCGTCGAGGTCATCGCCGCCCACGCCAACCCCGAAACCAATGTCCT
GGTCACCAACCTGATCCTCGGCTTCCTCGTCAATATGGGCCTTGGCGCCGTCGTCGGCGCGCTCGGTGGCCTTGCCATCG
TGCGTCTCGTCGACCGGCTCAATCTCGACCACGGCCTGCTGCCGATCTTCGTGCTGACCCTGTCACTGATGGTCTTCGCC
GCCGCCGGCGCCATCGGCGGCTCGGGCTTCCTGGCGGTCTATATCGCCGGCCTCATTGCCGGCAATTCCGACATCCGCGC
CGTCACCATCCTCAAGCGCTTCCAGGACGGCATGTCGTGGCTGGCGCAGATCATCATGTTCCTGATCCTCGGCCTGTTCG
CCACCCCCTCGCAATTTCCGGCGATCATGGTGCCGGCGATAGCGCTTGGCCTGTTCCTGATGTTTGTCGCCCGCCCGATC
GCTGTCTGGCTCTGCCTGATCCCGTTCCGCCTGCCGCGCCCCGAAGTCGCCTTCGTCTCCTGGGTCGGCCTGCGCGGCGC
CGTCTCGATCCTGCTCGCCATCACACCGCTGCTCGGCGGGCTGGAGAACGGCCGCACCATCTTCAACGCCGCCTTCATCA
TCGTACTGGTGTCGCTGGTCATCCAGGGCTGGACCGTCGGACCGCTGGCGCGTCGCCTCGGTCTCATCGTGCCGGCGCGC
CTTGGACCGCTGGACAAGGTCGAGCTGGAATTGCCGGGCTCCGCCCATCACGAGCTTCTCGCCTATCGCGTGGCGCATGG
CAGCCCGGTGGCGCGCGGCGAGCGCATTCCGCGTTGGGCGCGGCCCTCGCTGGTGCTGCGCGACGGCCGCTCGATGCGCT
TTCAGGACATGGGCCGGCTCGCCGCCGGCGACCAGGTCTACATCTTCGTGCCGGACCGCTACCCGCGCCTGCTCGACAAG
CTGTTCGCCAGCCGCGCGGTGGTCGACCCGGAAGACGCCGATTTCTTCGGCGCCTTCGCCGTCGACCCGGCGCGCGCCGC
GGCCGAATTGGAGGCAGCGTACGCGCCGGGTCTGACCGAGGCGGAGCAGAAGCTCACCGTCGGCGCGCTGGTCACGGCGC
GGCTTGGCGGCCATGCCGAATACGCCGATCGCGTGCTGATCGGCTCGATCGAGCTGATCGTCAGGGATGTCGACGACAAG
GGCAGGATCACGGGTCTCGGTCTTTCCTTCGAGCCGACCGCGCCGGTGGCGCGGGTGCCGGTGTTCCTGAGCGCCGGCGA
GATGGGCGACCGCCTCGGCGCCTTCATCCGCAATTGGCGCAAGCCGACCGAGACGCAGGAAGCGGCAGCACAGGCCGAAG
ACGCCCCCAAGCCGCCGGTTGAAAAAGCCACGACCGGGAGCTGA

Protein sequence :
MEHAIYLVTLVGTALVVAAAFSSLIAFRFGAPLLLLFLCIGLATGTDGLGIEFDNARIAYFAGSLALAVILFDSGFGTPL
NALRQAAGPALSLATFGVLLTTGLFGAAAYYLLDLTWLESFLLGAAVASTDAAAVFFLLRAGEINLRERVRSTLEVESGT
NDPIAIFLTITLVEVIAAHANPETNVLVTNLILGFLVNMGLGAVVGALGGLAIVRLVDRLNLDHGLLPIFVLTLSLMVFA
AAGAIGGSGFLAVYIAGLIAGNSDIRAVTILKRFQDGMSWLAQIIMFLILGLFATPSQFPAIMVPAIALGLFLMFVARPI
AVWLCLIPFRLPRPEVAFVSWVGLRGAVSILLAITPLLGGLENGRTIFNAAFIIVLVSLVIQGWTVGPLARRLGLIVPAR
LGPLDKVELELPGSAHHELLAYRVAHGSPVARGERIPRWARPSLVLRDGRSMRFQDMGRLAAGDQVYIFVPDRYPRLLDK
LFASRAVVDPEDADFFGAFAVDPARAAAELEAAYAPGLTEAEQKLTVGALVTARLGGHAEYADRVLIGSIELIVRDVDDK
GRITGLGLSFEPTAPVARVPVFLSAGEMGDRLGAFIRNWRKPTETQEAAAQAEDAPKPPVEKATTGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 8e-56 42
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 8e-56 42