Gene Information

Name : thyA (mll1467)
Accession : NP_103049.1
Strain : Mesorhizobium loti MAFF303099
Genome accession: NC_002678
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1220831 - 1221625 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGCCAATATCTCGACCTCTTGCAGCATGTGCTGGACAACGGTGCCGACCGTAGCGACCGCACCGGCACCGGCACGCG
CTCCGTCTTTGGCTACCAGATGCGTTTCGACCTGGCGCGCGGTTTTCCGGTCACTACGACCAAGAAGCTGCACCTGAAGT
CGATCATCCATGAACTCCTGTGGTTCCTGGCCGGCGACACCAACATCAAATACCTGACTGACCATGGCGTCACGATCTGG
GACGAATGGGCCGACGAGAATGGCGACCTTGGTCCCGTCTACGGCAGGCAGTGGCGCTCCTGGCCGGACGGTCATGGCGG
CTCGATCGACCAGATCGCGGGCCTTCTCAAGGAGATACGCCGCAATCCTCAATCGCGGCGGCTGATCGTTTCGGCGTGGA
ACCCGGCCGAGGTGGAGGCGATGGCGCTGCCGCCCTGCCACTGCCTGTTCCAGTTCTACGTGTCCGAGGGCCGGCTGTCC
TGCCAGCTCTACCAGCGGTCGGCCGATATTTTCCTCGGCGTGCCCTTCAACATCGCGTCCTACGCGCTGCTGACGCTGAT
GGTGGCGCAGGTGACCGGGCTGAAGCCGGGCGATTTCGTCCACACGCTGGGCGACGCGCATCTCTATTCGAACCATTTCG
AACAGGCGCGCGAGCAGTTGCAGCGCACGCCAAGGGCATTGCCGACGATGTGGATCAATCCGGAGGTGAAGGACCTGTTC
GCCTTCCGCTTCGAGGATTTCCGGCTGGAAAACTACGTCGCCGACGCATCGATCCAGGCGCCGATCGCCGTTTGA

Protein sequence :
MRQYLDLLQHVLDNGADRSDRTGTGTRSVFGYQMRFDLARGFPVTTTKKLHLKSIIHELLWFLAGDTNIKYLTDHGVTIW
DEWADENGDLGPVYGRQWRSWPDGHGGSIDQIAGLLKEIRRNPQSRRLIVSAWNPAEVEAMALPPCHCLFQFYVSEGRLS
CQLYQRSADIFLGVPFNIASYALLTLMVAQVTGLKPGDFVHTLGDAHLYSNHFEQAREQLQRTPRALPTMWINPEVKDLF
AFRFEDFRLENYVADASIQAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 7e-73 60