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Name : serS (ML0082) Accession : NP_301186.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 102122 - 103375 bp Length : 1254 bp Strand : + Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGATTGACCTGCAATTGCTCCGGGAAGACCCCGACGTGGTCCGCCGTTCCCAACTTAGCCGTGGCGAAGACCCGGCCTT GGTGGATGCCCTACTGACAGCCGACACTGCTCGTCGGGCCGCAATTTCGGCTGCAGACTCGCTGCGTGCTGAACAGAAGG CCACCAGCAAAAGCTTGGGCGCGGCATCTGCCGAGGACCGTCCGGCGTTATTGGAGCGCGCAAAGGACCTCGCCGAGCAG GTGAAAGCCGCTGAAACCACCCAGGCTGAGACTGCGGCGGCATTCGCTGCAGCGTACATGGCAATTTCCAACGTCGTTCT GGATGGAGTGCCGACCGGCGGAAAGGACGACTACGCGGTACTGGATATTGTTGGCGATCCACCGCCTTTGAGCAATCCAA AGGACCACCTGGAACTCGGCGAAGCACTGGGCTTGATCGACATGCAGCGTGGTGCCAAAGTGTCCGGCTCGCGGTTCTAC TTCCTCACCGGTCGGGGTGCGCTGTTACAACTAGGCCTGTTGCAGCTTGCGTTGCGGCTTGCTGTCGAGAACGACTTTAT CCCAATGATCCCGCCCGTGCTGGTGCGCCCGGAGGTGATGTCTGGTACCGGATTTTTGGGCGCTCATGCCGAGGAGGTGT ATAGGGTAGACGATCTGTATCTGGTGGGCACCTCTGAAGTGCCAATGGCCGGCTATCACTCCGACGAAATCCTCGATCTA TCCGTTGGCCCGCTACGGTACGCGGGTTGGTCGTCGTGTTTCAGGCGCGAGGCCGGCAGCCACGGCAAGGACACTCGTGG CATCATCCGGGTGCACCAGTTCGACAAGGTGGAGGGGTTTGTCTACTGTGCACCCACCGACGCCGAGGTTGAACACCAAC GGCTGCTGGGTTGGCAGCGCGAGATGTTGGCGCGCATAGAGGTGCCATATCGGGTAATCGACGTGGCTGCGGGCGATCTC GGTTCGTCGGCGGCCCGCAAGTTCGATTGCGAGGCGTGGGTACCGACCCAGGGCAGCTACTGCGAGCTGACCTCGACGTC AAACTGCACCACCTTCCAGGCGCGCCGGCTAGCTACCCGCTACCGAGATGCCAGTGGCAAGCCACAGATCGTTGCCACAC TAAACGGCACGCTGGGTACCACCCGGTGGCTGGTCGCGATCTTGGAAAACCACCAGCGGCCCGACGGCAGCGTGCGGGTG CCGCCGGCTTTGGTACCTTTCGTCGGCACAGAGTTGCTAGAGTCGCCCCGCTGA Protein sequence : MIDLQLLREDPDVVRRSQLSRGEDPALVDALLTADTARRAAISAADSLRAEQKATSKSLGAASAEDRPALLERAKDLAEQ VKAAETTQAETAAAFAAAYMAISNVVLDGVPTGGKDDYAVLDIVGDPPPLSNPKDHLELGEALGLIDMQRGAKVSGSRFY FLTGRGALLQLGLLQLALRLAVENDFIPMIPPVLVRPEVMSGTGFLGAHAEEVYRVDDLYLVGTSEVPMAGYHSDEILDL SVGPLRYAGWSSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCAPTDAEVEHQRLLGWQREMLARIEVPYRVIDVAAGDL GSSAARKFDCEAWVPTQGSYCELTSTSNCTTFQARRLATRYRDASGKPQIVATLNGTLGTTRWLVAILENHQRPDGSVRV PPALVPFVGTELLESPR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 6e-46 | 41 |
