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Name : tkt (ML0583) Accession : NP_301494.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 707605 - 709704 bp Length : 2100 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : GTGACCACACTCGACCAGATCTCCACGCTGACCCAACCGCGCCATCCCGATGACTGGACCGAGATCGATTCGGCTGCAGT CGACACCATCAGGGTGTTGGCTACCGACGCGGTCCAAAAAGCTGGCAACGGGCACCCGGGGACGGCGATGAGCTTGGCCC CGCTGGCCTACACTTTGTTCCAGCGCACTCTACGCCACGACCCCAATGACACCGCATGGCTGGGTCGTGACCGATTCGTG CTGTCGGCCGGGCATAGCAGCCTGACCTTATATATACAACTCTATCTCGGCGGCTTCGGTCTCGAACTATCTGACATCGA ATCGCTGCGCACCTGGGGATCCACAACTCCTGGGCATCCAGAGTTCCGGCACACTAAGGGTGTTGAGATCACCACCGGCC CACTCGGCCAGGGTCTAGCATCAGCAGTCGGGATGGCGATGGCATCACGTTACGAACGTGGCCTGTTCGACCCCGACGCT GAACCGGGAGCCAGCCCTTTCGACCATTACATTTATGTGATCGCCTCCGACGGGGACATCGAAGAAGGGGTGACATCGGA AGCGTCGTCCCTGGCCGCAGTCCAGCAACTCGGCAACCTCATCGTGTTCTACGACCACAACCAGATCTCGATCGAAGGCG ACACCAAAATCACGCTGTGCGAGGACACCGCCGCACGCTACCGCGCCTACGGCTGGCACGTACAAGAGGTGGAAGGTGGC GAGAACGTCGTCGGCATTGAGGAAGCCATCGCCAACGCGAAAGCCGCCACCGACCGGCCGTCGTTCATCTCACTGCGCAC CATCATCGGTTATCCCGCGCCAACCTTGATAAACACCGGCAAAGCGCACGGTGCGGCCCTTGGCGAAGACGAGGTAGCGG CCACTAAGCGAATCCTTGGGTTCGATCCCGACAAGACCTTTGCAGTCCGCGAGGACGTAATCACCCACACCCGCGGCTTG ATAGCCCGCGGCAAAGAAGCCCACGAACGCTGGCAACTAGAATTCGAAGCGTGGGCACAGCGCGAGCCCGAACGCAAGGC ACTGTTGGATCGGTTGCTCGCCCAGCAGCTTCCCGACGGCTGGGATGCTGACCTGCCGAACTGGGAGCCGAGGTCCAAGG AATTGGCCACCCGCGCCGCATCTGGTGCGGTACTATCCGCGATAGGACCGAAACTCCCGGAGTTGTGGGGCGGGTCGGCC GATCTAGCGGGCAGCAACAACACCACCATAAAAGACGTTGATTCCTTTGGGCCGCCGTCGATTTCGACCGACGAGTACAC CGCACATTGGTATGGTCGCACCTTGCATTTCGGTGTTCGCGAACACGCGATGGGCGCCATTCTGTCCGGCATCGTGCTGC ACGGCCCCACCCGCGCATATGGTGGTACATTTCTACAATTCTCCGACTACATGCGCCCGTCGGTGCGACTGGCGTCGTTG ATGGATATTGACACGATCTACGTGTGGACGCACGATTCGGTCGGACTCGGCGAGGACGGCCCAACCCATCAGCCCATCGA ACACCTCGCAGCGTTGCGTGCTATCCCTCGATTGTCGGTGGTGCGTCCCGCCGATGCCAACGAAACGGCATATGCCTGGC GCACAATCCTGGCTCGCGGCGCCAACAGCGGTCCGGTCGGGCTAATCCTGACCCGGCAGAGTGTGCCAGTGTTGGAAGGC ACCAACACCGAAGGCGTCGCCCGAGGCGGCTATGTGCTAGGCGATGGTGGCAGCTCTGAAGCTAAGGAGCCTGACGTCAT TTTGATCGCCACCGGATCCGAGGTCCAACTCGCTGTCGCAGCTCAGAAGTTGTTGGCGGATAAAGACATCATTGTGCGGG TGGTGTCGATGCCGTGTGTGGAATGGTTCGAGTCACAGCCGTACGAGTATCGCGACAGTGTGTTGCCCCCGTCAGTGTCG GCACGGGTGGCCGTCGAGGCCGGCGTCGCGCAATGCTGGCATAAGCTGGTCGGAGACACCGGCAAGATTGTGTCCATCGA GCACTACGGCGAATCCGCAGATTACCAGACTTTGTTCCGTGAGTACGGCTTCACGCCGGAGGCCGTGGTTGCCGCAGCGG AACAGGTATTGGATAACTGA Protein sequence : MTTLDQISTLTQPRHPDDWTEIDSAAVDTIRVLATDAVQKAGNGHPGTAMSLAPLAYTLFQRTLRHDPNDTAWLGRDRFV LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSTTPGHPEFRHTKGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNQISIEGDTKITLCEDTAARYRAYGWHVQEVEGG ENVVGIEEAIANAKAATDRPSFISLRTIIGYPAPTLINTGKAHGAALGEDEVAATKRILGFDPDKTFAVREDVITHTRGL IARGKEAHERWQLEFEAWAQREPERKALLDRLLAQQLPDGWDADLPNWEPRSKELATRAASGAVLSAIGPKLPELWGGSA DLAGSNNTTIKDVDSFGPPSISTDEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPSVRLASL MDIDTIYVWTHDSVGLGEDGPTHQPIEHLAALRAIPRLSVVRPADANETAYAWRTILARGANSGPVGLILTRQSVPVLEG TNTEGVARGGYVLGDGGSSEAKEPDVILIATGSEVQLAVAAQKLLADKDIIVRVVSMPCVEWFESQPYEYRDSVLPPSVS ARVAVEAGVAQCWHKLVGDTGKIVSIEHYGESADYQTLFREYGFTPEAVVAAAEQVLDN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 7e-113 | 43 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 2e-115 | 42 |
