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Name : thiC (ML0294) Accession : NP_301331.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : thiamine biosynthesis protein ThiC Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0422 EC number : - Position : 377487 - 379130 bp Length : 1644 bp Strand : + Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine DNA sequence : ATGACTGAAACCTTGTCGAAAACCACTGAACCATCCGTAACCACCGGACCGATCCCTGGAAGCAGCAAGGCTTACCGAGA AGTAGCGAACCCGGATGGCGGACCTAGCCTGCGGGTACCGTTCCGCCGAGTACATCTATCCACCGGCGCCCATTTCGACC TTTACGACACTTCCGGGCCCTACACCGATCCCGATGCGGTGATCAACCTGACGGCCGGGTTGCCGCCCAGGCCCGGCGTG ATCCGTGACCGTGGCACACAACTGCAGCGGGCCCGTGCCGGAGAGATTACTGCGGAGATGGCGTTCATCGCTGACCGCGA GGGCATGCCCGCCGAGTTGGTGCGCGTCGAGGTCGCCCTTGGCCGCGCGGTGATTCCTGCCAACCACAACCATCCTGAGA TCGAGCCGATGATCATCGGTAAGGCATTTGCGGTCAAAGTCAACGCAAACATCGGCAATTCGGCGGTGACATCGTCGATC GCCGAGGAGATCGACAAGATGGTGTGGGCCACTCGCTGGGGTGCAGACACAATCATGGACCTGTCCACCGGCAAGAACAT TCACGAAACGCGTGAGTGGATCCTGCGCAATTCGCCGGTGCCGGTCGGCACTGTGCCGATCTATCAGGCGTTGGAAAAAG TCAAGGGCGATCCAACCAAGCTAACTTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGTGAACAGGGTGTGGATTAC ATGACCGTGCACGCCGGTGTGCTACTGCGATATGTACTGTTGACCGCAAAGCGGGTCACCGGCATCGTGTCCCGCGGTGG GTCAATCATGGCGTCCTGGTGTTTAGCCAATCATCGGGAGTCGTTCTTGTACACAAACTTTGCGGAGCTCTGCGATATCT TCGCGCGCTACGACGTCACTTTCTCGCTTGGTGACGGACTGCGACCCGGCTCAATCGCCGACGCCAACGACACTGCACAG TTCGCCGAGTTGCGCACTCTGGGGGAGCTATCAAAGATCGCGAAAGTCCATGGTGCACAGGTCATGATCGAGGGACCAGG ACACATCCCGATGCATAAGATTGTGGAGAACGTGCGGCTAGAAGAGGAACTGTGCGAGGAGGCACCGTTTTACACGCTGG GCCCGTTGGCCACCGATATCGCACCGGCCTATGATCACATCACGTCGGCGATTGGCGCGGCTGTTATCGCCCAAGCCGGT ACCGCGATGCTGTGCTATGTAACCCCGAAAGAGCATCTGGGTCTGCCAGACCGCAAGGACGTCAAGGACGGCGTGATCGC CTACAAGATCGCCGCGCATGCAGCGGACCTGGCCAAGGGCTATCCTCGCGCGCAGGAACGTGACGATGCACTGTCCACGG CACGGTTCGAATTCCGCTGGAACGACCAATTCGCACTATCGCTTGATCCCCCCACCGCACGAGAGTTCCACGACGAGACG TTGCCGGCCGAGCCGGCTAAGACGGCGCACTTCTGTTCGATGTGTGGGCCGAAATTCTGCTCTATGCGGATCACCGCTGA TATACGAGTATATGCGGCCAAGCACGGACTCGACACTGAAGAAGCCATCGAGATGGGGATGACGGAGAAATCAGCCGAGT TCGCCGAGCACGGCAATCGTGTGTATCTGCCGCTCACGCAGTGA Protein sequence : MTETLSKTTEPSVTTGPIPGSSKAYREVANPDGGPSLRVPFRRVHLSTGAHFDLYDTSGPYTDPDAVINLTAGLPPRPGV IRDRGTQLQRARAGEITAEMAFIADREGMPAELVRVEVALGRAVIPANHNHPEIEPMIIGKAFAVKVNANIGNSAVTSSI AEEIDKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTKLTWEIYRDTVIEQCEQGVDY MTVHAGVLLRYVLLTAKRVTGIVSRGGSIMASWCLANHRESFLYTNFAELCDIFARYDVTFSLGDGLRPGSIADANDTAQ FAELRTLGELSKIAKVHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAVIAQAG TAMLCYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGYPRAQERDDALSTARFEFRWNDQFALSLDPPTAREFHDET LPAEPAKTAHFCSMCGPKFCSMRITADIRVYAAKHGLDTEEAIEMGMTEKSAEFAEHGNRVYLPLTQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| BJAB07104_00317 | YP_008207782.1 | Thiamine biosynthesis protein ThiC | Not tested | AbaR25 | Protein | 2e-156 | 67 |
| BJAB0868_00321 | YP_008211647.1 | Thiamine biosynthesis protein ThiC | Not tested | AbaR26 | Protein | 2e-156 | 67 |
