Gene Information

Name : purA (ML0280)
Accession : NP_301321.1
Strain : Mycobacterium leprae TN
Genome accession: NC_002677
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 361950 - 363248 bp
Length : 1299 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGCCGGCAGTCGTCCTCATCGGCGCTCAGTGGGGCGACGAGGGCAAAGGTAAGGTCACAGACCTGCTCGGCGGACGTGC
CCAGTGGGTGGTGCGCTATCAGGGTGGCAATAACGCTGGGCATACCGTTGTCTTGCCTACTGGCGAGAACTTCACACTGC
ATCTGATCCCGTCGGGGGTGCTGACGCCGGGTGTTACCAACGTCATCGGTAACGGTGTGGTGGTGGATCCCGGAGTGCTG
CTCAGCGAACTGCAAGGCCTGGAAGATCGTGGTGTCGACACCTCCCAGCTGCTGATCTCAGCCGATGCGCACCTGCTGAT
GCCCTACCACGTGGCCATCGACAAGGTCACCGAGCGTTACATGGGCAACAAGAAGATCGGCACTACCGGCCGCGGTATCG
GGCCCTGTTACCAGGACAAGATCGCCCGCATGGGGATACGGGTCGCCGATGTCTTAGAACCTGGTGAGTTGACCCACAAG
ATCGAGGCTGCGCTCGAGTTCAAAAACCAGGTGTTGGTCAAGATCTACAACCGCAAGGCGTTGGACCTGGCTCAGGTTGT
CGAAACGCTGCTGGAGCAGGCGCAGCAATTTCGACATCGCATCACCGACACTCGTCTGTTGCTCAACGACGCCCTCGAGG
CCGGTGAGACGGTGCTGCTTGAAGGCGCACAAGGCACCCTGCTCGACGTTGATCACGGCACCTACCCGTATGTGACATCG
TCGAATCCGACGGCGGGCGGTGCGGCGTTGGGCTCCGGTATCGGACCGACCCGGATCCACACTGTGCTAGGCATTCTCAA
GGCCTACACTACTCGGGTGGGTTCTGGTCCTTTCCCTACCGAACTGTTCGACGAGAACGGCGAGTACTTGGCCAAGACTG
GTAGCGAGATCGGCGTGACGACAGGACGACGGCGGCGTTGCGGGTGGTTCGACGCCGTGATAGCCCGCTACGCCACCCGG
GTCAACGGGATCACCGACTATTTCCTGACCAAGCTTGACGTGCTGTCCAGCTTGGAAACGGTGCCGGTCTGCGTCGGCTA
TCAGATCGCCGGTGTGCGCACCCACGATATGCCGATAACCCAAAGCGATCTCGCCCGTGCCGAGCCGATCTATGAGGAGC
TGCCGGGTTGGTGGGAAGACATCTCCGGAGCGCGGGAATTCGAGGACCTGCCCGCCAAAGCGCGTGACTACGTATTGAGA
CTGGAAGAACTTGCTGGAGCACAGGTTGCGTGCATAGGTGTCGGTCCGGGACGGGATCAGACCATCGTGCGATGCGATGT
ATTGAGGAGCCGTCGGTGA

Protein sequence :
MPAVVLIGAQWGDEGKGKVTDLLGGRAQWVVRYQGGNNAGHTVVLPTGENFTLHLIPSGVLTPGVTNVIGNGVVVDPGVL
LSELQGLEDRGVDTSQLLISADAHLLMPYHVAIDKVTERYMGNKKIGTTGRGIGPCYQDKIARMGIRVADVLEPGELTHK
IEAALEFKNQVLVKIYNRKALDLAQVVETLLEQAQQFRHRITDTRLLLNDALEAGETVLLEGAQGTLLDVDHGTYPYVTS
SNPTAGGAALGSGIGPTRIHTVLGILKAYTTRVGSGPFPTELFDENGEYLAKTGSEIGVTTGRRRRCGWFDAVIARYATR
VNGITDYFLTKLDVLSSLETVPVCVGYQIAGVRTHDMPITQSDLARAEPIYEELPGWWEDISGAREFEDLPAKARDYVLR
LEELAGAQVACIGVGPGRDQTIVRCDVLRSRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 2e-104 53