Gene Information

Name : clpC (ML0235)
Accession : NP_301295.1
Strain : Mycobacterium leprae TN
Genome accession: NC_002677
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 306003 - 308549 bp
Length : 2547 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAAAGATTTACCGATCGTGCCCGCAGGGTGGTCGTCCTGGCACAGGAAGAGGCCCGGATGCTCAACCATAACTA
CATCGGCACCGAGCACATTTTGCTGGGTCTTATCCACGAAGGCGAAGGTGTCGCGGCGAAATCGTTGGATTCGTTGGGGA
TTTCACTTGAAGCCGTTCGCAGTCAGGTCGAAGATATTATCGGCCAGGGTCAGCAGGCGCCGTCGGGGCATATCCCGTTT
ACGCCTCGTGCCAAGAAGGTTCTTGAGCTGAGCTTGCGTGAGGCGCTGCAGCTCGGCCATAATTACATCGGCACCGAGCA
CATTTTGCTGGGCCTTATCCGGGAGGGAGAGGGTGTGGCCGCCCAGGTGCTGGTCAAGTTGGGCGCCGAGCTGACCCGAG
TGCGCCAGCAGGTGATCCAGCTGCTAAGTGGCTACCAGGGCAAAGAAGCTGCTGAAGCGGGCACTGGAGGCCGGGGTGGC
GAATCCGGTAGTCCATCTACATCTCTGGTGCTCGACCAGTTCGGTCGAAACCTGACGGCTGCTGCGATGGAGAGCAAGCT
GGATCCGGTCATTGGCCGCGAAAAGGAAATCGAGCGGGTGATGCAGGTGCTGAGCCGGCGCACCAAGAACAACCCGGTGT
TGATCGGCGAGCCTGGCGTCGGCAAGACCGCTGTCGTCGAGGGTCTTGCGCAGGCCATCGTGCACGGTGAGGTTCCCGAG
ACGCTGAAAGACAAGCAGCTTTACACACTTGACCTGGGCTCGTTGGTAGCCGGCTCGCGCTACCGCGGTGACTTCGAGGA
GCGCCTGAAGAAGGTACTCAAGGAGATCAACACCCGCGGTGACATAATCTTGTTCATCGATGAGCTGCACACCCTGGTAG
GTGCCGGTGCCGCCGAGGGGGCGATCGATGCCGCGTCGATCCTCAAGCCCAAGCTGGCCCGCGGTGAGCTGCAAACCATT
GGCGCTACCACCCTCGACGAATATCGCAAGTACATCGAGAAAGACGCCGCCCTGGAGCGCCGCTTCCAGCCGGTGCAGGT
GGGTGAGCCAACGGTGGAGCACACTATCGAGATTCTCAAGGGCCTGCGGGACCGCTACGAGGCCCACCATCGGGTGTCGA
TCACCGACTCGGCGATGGTGGCCGCCGCCACTCTGGCCGATCGCTACATCAATGACCGATTCCTCCCGGACAAGGCGATC
GACCTGATTGACGAAGCAGGCGCCCGGATGCGGATTCGCCGAATGACCGCGCCACCAGATCTGCGTGAGTTCGACGAGAA
GATCGCCGAAGCCCGCCGGGAGAAAGAGTCGGCGATCGACGCCCAGGATTTCGAGAAGGCGGCTAGCCTACGCGACCGGG
AGAAGCAACTGGTAGCTCAGCGTGCAGAACGCGAAAAGCAATGGCGTTCAGGCGATCTCGATGTTATTGCGGAAGTTGAC
GACGAGCAAATTGCCGAGGTGCTGGGCAACTGGACCGGTATACCGGTGTTCAAGCTCACCGAGGCTGAGACTACCCGGCT
GCTCCGTATGGAGGAGGAGCTGCACAAACGGATTATCGGCCAGGAGGATGCTGTTAAGGCCGTGTCCAAGGCGATCCGTC
GTACCCGCGCCGGGCTAAAAGACCCCAAGCGCCCGTCGGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACT
GAACTGTCTAAGGCGCTGGCCAACTTTTTGTTTGGCGACGACGACGCGCTCATCCAGATCGATATGGGCGAGTTCCACGA
CCGGTTCACCGCGTCGCGGCTTTTTGGTGCTCCGCCGGGATACGTCGGCTACGAGGAGGGCGGTCAGCTCACCGAGAAGG
TGCGGCGCAAGCCGTTCTCGGTGGTGCTGTTCGACGAGATCGAAAAAGCGCATCAGGAGATCTATAACAGCCTGTTGCAG
GTGCTTGAAGACGGGCGGCTCACCGATGGGCAGGGTCGCACGGTGGACTTCAAAAACACCGTGCTGATCTTTACATCCAA
CCTTGGTACCTCCGACATCTCCAAGCCGGTCGGTCTGGGCTTCACCCAAGGTAGTGGTGAGAACGACTACGAGCGGATGA
AGCAGAAGGTCAACGATGAGCTGAAGAAGCACTTCCGCCCAGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAACTGAGCCGTGATGAGATCATCCGGATGGTCGATCTCATGATTAGCCGGGTTGCTAACCAGCTCAAGGTCAAAGACAT
GACGCTGGAGTTGACAAACAAGGCTAAGGCCTTGTTGGCTAAGCGTGGCTTCGATCCGGTGCTGGGTGCTCGCCCGCTGC
GGCGTACTATCCAACGCGAGATCGAGGACCAGCTCTCGGAGAAGATCCTCTTCGAGGAAGTCGGGCCGGGACAGGTCGTC
ACCGTCGACGTCGACAACTGGGATGGCGAAGGCCCCGGTGAGGACGTGAAGTTCACTTTCACTGGGATCCGCAAGCCGTC
GACAGAGCCGGATCTGGCTAAGGCCGGAGTGCACAGCGCTGGCGGGCCTGAGCCGGTCGAGCAGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLDSLGISLEAVRSQVEDIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVIAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGSGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLSRDEIIRMVDLMISRVANQLKVKDMTLELTNKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVV
TVDVDNWDGEGPGEDVKFTFTGIRKPSTEPDLAKAGVHSAGGPEPVEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC NP_301295.1 ATP-dependent Clp protease VFG0079 Protein 0.0 60
clpC NP_301295.1 ATP-dependent Clp protease VFG0080 Protein 3e-144 51