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Name : lysS (ML0233) Accession : NP_301293.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 303740 - 305263 bp Length : 1524 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : GTGAACGCTGACCCGTTGGAGACTGACGCTGCTCTTCCTGAGCAGTTTCGGATTCGCCGGGACAAGCGTGCTCGTTTGTT GGCGGAGGGGCGTGACCCGTATCCGGTCGCCATTGAACGCACCCATACCCTAGCTGAGGTTCGCGCAGCCTATCCCGACC TGGCGACCGACTCCGCCACCGATGACATCGTTGGTATCGCGGGTAGGGTAATATTCGCGCGTAATTCGGGGAAACTGTGC TTTGCGACACTGCAGGACGGTGACGGCACCAACTTGCAGGTGATGATTAGTCTCAACAAGGTTGGTTCCGAAACGCTTGA CGCGTGGAAAGTCGACGTCGATCTTGGCGACATTGTTTATGTACACGGGAACGTGATTAGCTCGCGTAGCGGCGAGTTAT CAGTTCTTGCTGATTCCTGGCAGATGGTATCTAAGTCGTTGCGGCCACTGCCCGTCGCGCATAAAGAGATGAGTGAAGAG TCGCGGGTGCGACAGCGTTATGTTGACCTTATTGTCTGTCCGCAAGTGCGAATAGTAGCTCATCAGAGAATTGCCGTTAT CCGCGCCATACGGACTGCGTTAGAACGACGCGGTTTTCTCGAAGTTGAGACGCCTATGTTGCAGACTCTGGCCGGTGGCG CTGCGGCCCGGCCATTCGTCACACATTCCAATGCCCTGGACATCGATCTGTACCTGCGTATCGCACCTGAACTGTTCCTC AAGCGATGCATCGTCGGTGGTTTCGACAAGGTCTTCGAACTTAATCGAGTGTTTCGAAACGAAGGCGCCGATTCTACGCA TTCCCCGGAATTTTCCATGCTAGAGACCTACCAGACCTACGGAACCTATGACGATTCGGCGGTCGTTACCCGAGAAATTA TTCAAGAGGTGGCCGATGAGGCGATCGGGACCAGACAACTGCAGATGCCTGATGACAGCGTCTACGACATAGATGGAGAA TGGGAGACGATACAAATGTATCCGTCTCTGTCGGCTGTGTTGGGTGAAGAAATCACGCCGCAGACGTCAGTCGATCGGCT GCGAGCCATCGCGGATCGGCTTGGCCGTGGGATTGGTCCAGAGATTCTTGACAAGCCCAGTTACGGACATGGAAGACTCG TCGAGCAACTGTGGGAGTACACAGTGGGCAACACCCTGAGCGCGCCCACATTTGTCAAAGATTTTCCGGTCGAAACAACT CCTTTGACCCGTCAGCATCGAAGCATCCCCGGAGTGACCGAGAAGTGGGATCTCTACCTGCGTGGAGTTGAACTGGCCAC GGGGTACTCCGAATTAAACGATCCGGTCGTGCAGCGGGAAAGATTTGGTCAACAAGTCCGTGCTGCAGCCGCCGAGGAAG ATGAGGCGATGGCACTTGATGAGGAATTTCTGGCGGCACTGGAGTACGCGATGCCGCCATGCACTGGAACTGGAATGGGT ATCGACCGGTTGTTGATGTCTTTGACTGGACTGTCAATTAGGGAGACTGTTTTGTTCCCGATTGTTCGGCCGCACTCCAA CTGA Protein sequence : MNADPLETDAALPEQFRIRRDKRARLLAEGRDPYPVAIERTHTLAEVRAAYPDLATDSATDDIVGIAGRVIFARNSGKLC FATLQDGDGTNLQVMISLNKVGSETLDAWKVDVDLGDIVYVHGNVISSRSGELSVLADSWQMVSKSLRPLPVAHKEMSEE SRVRQRYVDLIVCPQVRIVAHQRIAVIRAIRTALERRGFLEVETPMLQTLAGGAAARPFVTHSNALDIDLYLRIAPELFL KRCIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTREIIQEVADEAIGTRQLQMPDDSVYDIDGE WETIQMYPSLSAVLGEEITPQTSVDRLRAIADRLGRGIGPEILDKPSYGHGRLVEQLWEYTVGNTLSAPTFVKDFPVETT PLTRQHRSIPGVTEKWDLYLRGVELATGYSELNDPVVQRERFGQQVRAAAAEEDEAMALDEEFLAALEYAMPPCTGTGMG IDRLLMSLTGLSIRETVLFPIVRPHSN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 2e-143 | 59 |
