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Name : metB (ML2394) Accession : NP_302550.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 2863794 - 2864960 bp Length : 1167 bp Strand : - Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine DNA sequence : ATGAGCGAAGATTACCGGGGACACCACGGCATTACCGGACTAGCCACCAAAGCCATCCATGCTGGCTATCGTCCGGATCC GGCAACAGGGGCAGTGAATGTCCCGATTTATGCCAGTAGTACTTTTGCCCAAGATGGCGTCGGTGAGTTGCGTGGCGGAT TCGAATACGCGCGTACCGGCAACCCCATGCGCGCCGCTTTAGAGGCATCCTTGGCCACGGTCGAAGAGGGCGTTTTTGCG CGAGCCTTCAGTTCCGGAATGGCTGCTAGCGACTGTGCCTTGCGGGTCATGCTGCGGCCGGGGGACCACGTGATCATCCC GGATGACGTCTACGGCGGCACCTTCCGGCTGATAGACAAGGTCTTTACTCAATGGAACGTTGACTACACGCCGGTACCGC TGTCTGATTTGGACGCGGTCCGCGCCGCGATCACATCACGGACCCGGCTGATATGGGTGGAAACACCGACCAATCCGCTG CTGTCCATCGCAGATATCACCAGCATCGGCGAACTAGGCAAAAAGCACTCAGTAAAGGTGTTGGTGGACAACACCTTTGC TTCACCCGCGCTGCAACAGCCGCTGATGCTGGGGGCAGACGTCGTGTTGCACTCGACCACAAAGTACATCGGCGGCCACT CTGATGTGGTGGGCGGCGCGCTAGTCACCAACGACGAAGAGCTGGACCAGGCTTTCGGCTTCTTGCAGAACGGAGCCGGT GCGGTGCCGAGCCCGTTCGACGCGTACCTAACGATGCGCGGATTGAAGACTTTAGTGCTGCGGATGCAGCGGCACAACGA AAATGCCATTACTGTAGCGGAATTCCTGGCTGGGCATCCGTCGGTGAGCGCCGTGCTGTATCCGGGCTTGCCCAGCCATC CCGGGCATGAGGTCGCTGCACGGCAGATGCGCGGCTTCGGCGGCATGGTTTCGTTGCGGATGCGAGCCGGCCGACTAGCC GCCCAGGATCTGTGTGCCCGCACCAAGGTGTTTACCTTGGCTGAATCCTTGGGTGGAGTGGAGTCGCTGATTGAGCAGCC CAGTGCCATGACGCACGCGTCGACAACCGGGTCGCAATTGGAAGTACCCGACGACCTGGTGCGGCTTTCGGTCGGTATTG AAGACGTCGGCGACCTGCTGTGCGACCTCAAGCAGGCGTTAAACTAA Protein sequence : MSEDYRGHHGITGLATKAIHAGYRPDPATGAVNVPIYASSTFAQDGVGELRGGFEYARTGNPMRAALEASLATVEEGVFA RAFSSGMAASDCALRVMLRPGDHVIIPDDVYGGTFRLIDKVFTQWNVDYTPVPLSDLDAVRAAITSRTRLIWVETPTNPL LSIADITSIGELGKKHSVKVLVDNTFASPALQQPLMLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQAFGFLQNGAG AVPSPFDAYLTMRGLKTLVLRMQRHNENAITVAEFLAGHPSVSAVLYPGLPSHPGHEVAARQMRGFGGMVSLRMRAGRLA AQDLCARTKVFTLAESLGGVESLIEQPSAMTHASTTGSQLEVPDDLVRLSVGIEDVGDLLCDLKQALN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-76 | 46 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-77 | 46 |
| metB | YP_281510.1 | cystathionine beta-lyase | Not tested | Not named | Protein | 1e-58 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | NP_302550.1 | cystathionine gamma-synthase | BAC0207 | Protein | 2e-65 | 43 |
