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Name : guaB1 (ML2066) Accession : NP_302378.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : inosine 5-monophosphate dehydrogenase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0516 EC number : 1.1.1.205 Position : 2453700 - 2455136 bp Length : 1437 bp Strand : + Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate DNA sequence : ATGAGGTTTCTGGACGGGCACCAGCCCAGGTTCGACCTAACCTATAAAGACGTTTTCATCGTGCCACACCGGTCGGATGT TGCGTCGCGATTTGACGTCGATTTGTCAACCTATGACGGCTCCGGCACCACTATTCCCGTAGTGGTCGCCAACATGACCA CGGTGGCCGGGCAACGGATGGCAGAGACGGTAGCTCGCCGGGGCGGCTTAGTAATTTTACCGCAGGATCTGCCGATTGCA ACAGTGCAGCAGGCAGTGGAGTTCGTCAAGAGCCGTGACCTGGTTATCGATACCCCGGTGTTACTGACACCTAACGATTC GGTGTCCGACGCGACCACACTGATCCACAAGCGCGCGCACGGTGTTGCGGTGGTGGCCTTCGAAGGCCGCCCAATTGGTC TGGTGCGCGAATCGTCTTGCCTAGGTGTGGACCGCTTCACTCGGGTGCGGGATGTCGCGACTACCGACTTTGTAACCGCC CCGGTGGGCACCGATCCACGCAAGATCTTCGACCTGCTCGAACATGCCCCGATCGACGTCGCGGTGCTGACTAACGCCGA CGGCACGCTGGCCGGAGTACTGACCCGCACCGGGGCGATCCGCGCCGGCATCTACACCCCAGCCACCGATGCCCGCGGAC GGCTCCGCATCGGTGCTGCTGTCGGCATAAACGGCGATGTAGCCGGCAAGGCCCAGTCCCTCGCCGAGGCAGGTGTCGAT GTGCTGGTCGTCGACACCGCACACGGATACCAAGTCAAGACACTCGAGGCGATCAAATGCGTCGCATCGCTGAACTTGGG TGTGCCGTTGGTCGCGGGCAACGTGGTGTCGGCTGAAGGTACTCGCGAGCTACTCAACGCCGGGGCGACCATCGTCAAGG TCGGCGTCGGCCCAGGAGCAATGTGCACAACTCGGATGATGACCGGTGTTGGCCGACCGCAATTCTCAGCTGTACTCGAA TGTGCCTCTGCTGCAAGGAAACTCAATAGGCACGTGTGGGCTGATGGAGGAGTCCGCCATCCGCGTGACGTGGCGCTGGC GTTGGCCGCAGGAGCATCGAACGTGATGATCGGGTCGTGGTTCGCCGGGACTTATGAGTCACCCGGGGACCTCATGCGGG ACCGCCACGACCAACCGTACAAGGAAAGCTACGGCATGGCGTCCAAGCGAGCGGTGGTTGCCCGCACCGTTGCCGACAGC TCATTCGATCGCGCTCGCAAGGCGTTATTCGATGAAGGCATCTCGACCTCACGGATGGGGCTGGATCCCGACCACGGTGG TGTCGAGGACCTGATCGATCACATCACCTCCGGCGTGCGCAGCACCTGCACCTATGTCGGCGCGTCGACCCTGGCGGAGC TGCATGAGAAGGCTGTCGTCGGGGTGCAGTCAGCGGCGGGTTTCGCCGAGGGCCATCCACTGCCCTCGGGGTGGTGA Protein sequence : MRFLDGHQPRFDLTYKDVFIVPHRSDVASRFDVDLSTYDGSGTTIPVVVANMTTVAGQRMAETVARRGGLVILPQDLPIA TVQQAVEFVKSRDLVIDTPVLLTPNDSVSDATTLIHKRAHGVAVVAFEGRPIGLVRESSCLGVDRFTRVRDVATTDFVTA PVGTDPRKIFDLLEHAPIDVAVLTNADGTLAGVLTRTGAIRAGIYTPATDARGRLRIGAAVGINGDVAGKAQSLAEAGVD VLVVDTAHGYQVKTLEAIKCVASLNLGVPLVAGNVVSAEGTRELLNAGATIVKVGVGPGAMCTTRMMTGVGRPQFSAVLE CASAARKLNRHVWADGGVRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRHDQPYKESYGMASKRAVVARTVADS SFDRARKALFDEGISTSRMGLDPDHGGVEDLIDHITSGVRSTCTYVGASTLAELHEKAVVGVQSAAGFAEGHPLPSGW |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| CpC231_1472 | YP_005683835.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 3e-134 | 58 |
| CpI19_1479 | YP_005685921.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 3e-134 | 58 |
| cpfrc_01479 | YP_003783879.1 | hypothetical protein | Not tested | PiCp 5 | Protein | 2e-134 | 58 |
| Cp1002_1469 | YP_005681736.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 9e-135 | 58 |
