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Name : nrdE (ML1734) Accession : NP_302195.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit alpha Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0209 EC number : 1.17.4.1 Position : 2094324 - 2096405 bp Length : 2082 bp Strand : - Note : Catalyzes the rate-limiting step in dNTP synthesis DNA sequence : ATGTTGAATCTGTACGATGCGGACGGCAAGATCCAATTCGACAAGGACGTACTCGCGGCCCGCCAATTCTTCCTGCAGCA TGTCAATCAGAACACGGTCTTTTTCCATAACCAGGACGAGAAGCTGGACTATCTGATCCGCGAGAATTACTACGAGCGTG AGGTGCTCGATCAGTACTCGCGTAACTTTGTCAAGTCGCTGCTGGATCGTGCCTACGCCAAGAAGTTTCGGTTCTCAACG TTTCTTGGTGCGTTCAAGTATTATACCTCTTACACGCTGAAGACGTTCGACGGGAAGCGGTATTTAGAGCGCCTCGAAGA CCGGGTCTGCATGGTCGCACTCACGTTGGCGGCCGGTGACACCGGCTTGGCCGAGAAGCTCGTCGACGAGATCATCGACG GCCGATTCCAGCCAGCTACCCCAACTTTTTTGAACTCGGGCAAGAAACAACGCGGCGAACCGGTGAGCTGTTTTTTGCTG CGCATTGAGGATAACATGGAGTCGATCGGGCGATCGGTCAACTCCGCGCTACAGCTATCCAAGCGTGGCGGAGGAGTTGC TTTGCTGCTGAGCAACATTCGTGAGCATGGTGCACCGATCAAGAACATCGAACACCAGTCTTCGGGCGTAATTCCGATCA TGAAGTTGCTTGAAGATGCGTTCTCGTATGCCAATCAGTTGGGCGCCCGCCAAGGCGCTGGTGCGGTGTACCTGCATGCT CATCACCCTGACATCTACCGCTTCTTGGACACTAAGCGGGAGAATGCCGACGAGAAGATCCGGATCAAGACGCTGAGCCT GGGGGTGATAATTCCCGACATCACCTTTGAGCTGGCTAAGCGTAACGAAGACATGTACCTGTTCTCGTCGTACGACGTCG AGCGGGTTTACGAGGTGCCGTTCGCCGATATTTCGGTGACTGAGAAGTATTATGAGATGCTCGATGACGCACGCATCCGC AAGACCAAGATCAAGGCGCGGGAGTTTTTCCAGAAGCTGGCCGAGCTGCAGTTCGAGTCCGGTTACCCCTATGTCATGTT CGAGGACACGGTGAACCGGGCCAACCCCATTGAAGGTAAGATCACTCACTCGAATCTATGCTCGGAGATCCTGCAGGTGT CCACGCCGTCGTTGTTTAACGACGACTTGTCGTATGCCAAAGTGGGCAAGGACATTTCATGTAACCTGGGATCGCTGAAC ATTGCCAAGACGATGGACTCACCGGATTTCGCGCAGACGGTTGAGGTGGCGATTCGCGCGTTGACTGCGGTGAGCGACCA GACGCACATCAAGTCGGTGCCCTCGATCGAGCAGGGTAACAATGATTCCCACGCGATCGGGCTGGGGCAGATGAACCTGC ATGGCTACTTGTCCCGTGAAGGAATCTTCTACGGTTCCGAAGAGGGAGTCGATTTCACCAACATTTACTTCTATACGGTG TTGTTTCACGTGTTGCTGGCTTCGAACTCTATCGCGATCGAACGAGGTACCTTCTTCAAAGGTTTCGAGCGGTCCAAGTA CGCGTCGGGAGAGTTCTTCGACAAATACATCGAGCAGACGTGGGAGCCGAAGACCGATAAAGTGCGTCAGTTATTCGCTG AGGCAGCGATCCGTATTCCGACCCAAAACGACTGGAAGCGGCTGAAGGAGTTGGTGGTCGCACACGGCATCTACAACCAG AACCTGCAGGCGGTGCCGCCGACCGGATCGATCTCCTATATCAACCATTCGACGTCGTCGATCCACCCGATCGTGTCGAA AGTTGAGATCCGTAAGGAAGGAAAAATTGGCCGAGTTTACTATCCGGCGCCCTATATGACCAATGACAATCTGCAGTACT ACCAGGACGCTTATGAGATCGGGTACCAGAAGATCATCGACACATACGCGGCGGCCACCCAGCACGTCGACCAAGGGCTC TCACTGACGTTGTTCTTCAAAGACACCGCCACCACCCGGGACGTGAACAAGGCGCAGATTTATGCGTGGCGCAAGGGAAT CAAGACGCTGTATTACATTCGGCTGCGGCAGATGGCGCTGGAAGGCACCGAAGTCGAGGGCTGCGTGTCTTGCACGCTGT AA Protein sequence : MLNLYDADGKIQFDKDVLAARQFFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYSRNFVKSLLDRAYAKKFRFST FLGAFKYYTSYTLKTFDGKRYLERLEDRVCMVALTLAAGDTGLAEKLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLL RIEDNMESIGRSVNSALQLSKRGGGVALLLSNIREHGAPIKNIEHQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHA HHPDIYRFLDTKRENADEKIRIKTLSLGVIIPDITFELAKRNEDMYLFSSYDVERVYEVPFADISVTEKYYEMLDDARIR KTKIKAREFFQKLAELQFESGYPYVMFEDTVNRANPIEGKITHSNLCSEILQVSTPSLFNDDLSYAKVGKDISCNLGSLN IAKTMDSPDFAQTVEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLSREGIFYGSEEGVDFTNIYFYTV LFHVLLASNSIAIERGTFFKGFERSKYASGEFFDKYIEQTWEPKTDKVRQLFAEAAIRIPTQNDWKRLKELVVAHGIYNQ NLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLQYYQDAYEIGYQKIIDTYAAATQHVDQGL SLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCTL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1481 | YP_001800875.1 | ribonucleotide-diphosphate reductase subunit alpha | Not tested | Not named | Protein | 0.0 | 78 |
