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Name : thyA (ML1519) Accession : NP_302064.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 1833026 - 1833826 bp Length : 801 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : GTGCTGATAGCGACGCCATACGAGGATTTGCTGCGTCTCGTGCTTGACTGCGGCGTAGCCAAAATGGACCGCACCGGCAC CGGGACTCGCAGTCTGTTTGGTCAGCAGTTGCGTTACGACCTGTCGGTTGGGTTCCCGCTAGTTACGACGAAAAAGGTGC ACTTCAAATCGGTTGTCTACGAGTTGTTGTGGTTCTTGCGCGGCGACTCCAACGTCGCCTGGTTGCATGAGCATGGAGTT AATATCTGGGATGAGTGGGCTAGCAGCACAGGCGACCTCGGGCCGATTTATGGTGTGCAGTGGCGATCTTGGCCGACCTC TTCGGGTGATTACATCGACCAAATCAGCACCGCACTGGATTTGCTGCGTACCGAACCGGATTCTCGGCGCATCATTGTGT CGGCTTGGAATGTCGGTGAAATCCCGCAGATGGCGCTGCCACCATGTCACGCGTTTTTCCAATTCTACGTCGCTCAAGGC CGGCTGAGTTGCCAGCTGTACCAGCGCAGCGCCGACATGTTCCTTGGTGTGCCGTTCAACATCGCCAGTTACGCGCTTCT GACCCACATGATGGCCGCCCAGTCCGGTCTTTTGGTTGGTGAGTTCGTCTGGACGGGCGGTGATTGCCACATCTACGACA ACCATGTCGAGCAGGTACAGCTGCAGCTCAGCCGCGAACCCCGAGCATATCCAGAACTCTTTTTAGCGCAGCGTGATTCT ATCTTCGACTATGTCTACGAGGACGTCGTCGTCACGAATTATGATCCGCACCCGGCGATCAAAGCCCCAGTCGCGATATG A Protein sequence : MLIATPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFPLVTTKKVHFKSVVYELLWFLRGDSNVAWLHEHGV NIWDEWASSTGDLGPIYGVQWRSWPTSSGDYIDQISTALDLLRTEPDSRRIIVSAWNVGEIPQMALPPCHAFFQFYVAQG RLSCQLYQRSADMFLGVPFNIASYALLTHMMAAQSGLLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDS IFDYVYEDVVVTNYDPHPAIKAPVAI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 2e-93 | 71 |
