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Name : pykA (ML1277) Accession : NP_301922.1 Strain : Mycobacterium leprae TN Genome accession: NC_002677 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 1519741 - 1521159 bp Length : 1419 bp Strand : + Note : catalyzes the formation of phosphoenolpyruvate from pyruvate DNA sequence : GTGACGAGACGCGGGAAGATCGTCTGTACCCTTGGCCCTGCAACACAATCGGACGAGTTAATCCGGGCGCTGGTTGAAGC CGGAATGGACGTTGCCCGCATGAACTTCAGTCACGGCGATTACTCCGATCACAAGGCTGTTTACGATCGGGTGCGCGTCG CATCTGATGCAACCGGACGCGCGGTCGGCGTGCTCGCTGACCTGCAGGGCCCAAAGATCAGGCTGGGACGCTTTGCCACG GGGTCCACCTACTGGGCTGACGGTGAAACGGTAAGGATCACTGTGGCCGACTGCCACGGTAGCCACGACCGGGTATCAAC CACCTACAAGAATTTGGCCAGGGATGCGGTGGTCGGTGACCGGGTTCTGGTCGACGACGGCAAGGTCGGACTGGTGGTCT CGGCCATCGATGGCGACGACGTGGTCTGTACTGTCACTGAAGGCGGCCCGGTTAGCAACAACAAGGGCATGTCGTTGCCC GGGATGCACGTGTCTGCTCCGGCTTTGTCGGACAAGGACATCGAGGACCTCACGTTCGCGCTGAATCTCGGCGCCGATCT GGTCGCGCTGTCGTTTGTGCGCTCGCCGTCTGACGTTGAGCTGGTCCACAAGGCGATGGATCGCGTCGGGCGGCGTGTAC CGGTGATCGCCAAGCTGGAGAAGCCAGAAGCCGTCGATAACCTCGAAGCTATTGTGTTGGCATTCGATGCCATCATGGTG GCTCGCGGCGACCTGGGTGTCGAGCTGCCACTTGAAGAGGTCCCACTGGTGCAGAAGCGGGCAATCCAGATGGCAAGGGA GAATGCGAAACCCGTCATCGTGGCTACCCAGATGCTAGACTCGATGATCGAAAACTCCCGGCCGACCCGAGCTGAGGCCT CCGACGTCGCTAATGCGGTGCTCGACGGCGCCGACGCGCTCATGTTGTCTGAGGAAACGTCGGTGGGGAAGTACCCATTG GCAGCCGTGAAGACGATGTCGCGCATTGTGTGTGCGGTTGAGGAGAATTCCACGGCCGCGCCGCCGTTGACACACGTACC TCGCACGAAGCGGGGGGTGATCTCGTACGCTGCCCGCGATATCGGTGAAAGACTCGACGCTAAGGCCTTGGTTGCGTTCA CTCAATCCGGTGACACGGTGCGGCGACTGGCGCGTCTACATACCCCGCTGCCGCTGCTTGCCTTCACCGCGTGGCCAGAG GTGCGCAGCCAACTCGCTATGACTTGGGGCACCGAGACATTTCTCGTACCAAAGATGCTGTCCACTGACGGTATGATACG CCAGGTGGACAAGTCACTGCTCGAACTTGGTCGCTACAAGCGTGGTGACTTGGTGGTGATCGTCGCTGGCACGCCACCTG GCACAGTAGGATCGACCAACTTGATCCATGTGCACCGGATTGGGGAGGACGACGTATAG Protein sequence : MTRRGKIVCTLGPATQSDELIRALVEAGMDVARMNFSHGDYSDHKAVYDRVRVASDATGRAVGVLADLQGPKIRLGRFAT GSTYWADGETVRITVADCHGSHDRVSTTYKNLARDAVVGDRVLVDDGKVGLVVSAIDGDDVVCTVTEGGPVSNNKGMSLP GMHVSAPALSDKDIEDLTFALNLGADLVALSFVRSPSDVELVHKAMDRVGRRVPVIAKLEKPEAVDNLEAIVLAFDAIMV ARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTRAEASDVANAVLDGADALMLSEETSVGKYPL AAVKTMSRIVCAVEENSTAAPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPE VRSQLAMTWGTETFLVPKMLSTDGMIRQVDKSLLELGRYKRGDLVVIVAGTPPGTVGSTNLIHVHRIGEDDV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-62 | 41 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-63 | 41 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 5e-63 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykA | NP_301922.1 | pyruvate kinase | VFG0479 | Protein | 2e-63 | 41 |
