Gene Information

Name : kdsB (PM0858)
Accession : NP_245795.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1010061 - 1010837 bp
Length : 777 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGACAAATTTTACGGTCATTATCCCTGCACGTTATGCGTCAACACGTTTACCTGGGAAACCTTTAGCGGAGATTGCGGG
AAAACCGATGATTGCACATGTCTTTGAAAAGGCGATGCAGTCAGGTGCAAAACGCGTCATTGTTGCGACAGATCATGAAC
AAGTTGCGACAGTTGCACGAGGATTTGGCGCAGAAGTTTGCATGACATCTGAAACGCATCAGTCAGGAACTGAGCGATTA
GCTGAAGTGGTTGAGAAGTTAGGTATTGCGGAAGATGAAATCATTGTCAATATTCAAGGAGACGAACCCTTGATCCCACC
GGCAATTGTACGTCAAGTTGCTGAGAATTTAGCAAAATACCAAGTAAAAATGGCAAGTTTGGCGGTCAACATAACGGACC
CCGAAGAATTGTTCAATCCTAATGCGGTCAAAGTATTGACCGATCATGCCGGCTATGTGTTGTATTTTTCCCGTGCACCG
ATTCCATGGCATCGTGATCAATTTGCCTCTTTACCAAAAGAAAAAAGCACAAGAGGACAATTGGTCTTGTCCGATCACTA
TTTACGTCATATAGGTATTTATGCCTATCGTGCAGGTTTTATTAAACAGTATATTCAATGGCAACCGAGTGTATTAGAGC
AGATTGAAAGCTTAGAGCAATTACGAGTGTTATGGTATGGTGAAAAAATCCATGTAGAATTAGCGCGAGAAGTGCCGCCG
GTTGGCGTGGATACCGCTGAAGATTTAGAAAAAGTGCGGTCAATTTTAGAAAAATAA

Protein sequence : 
MTNFTVIIPARYASTRLPGKPLAEIAGKPMIAHVFEKAMQSGAKRVIVATDHEQVATVARGFGAEVCMTSETHQSGTERL
AEVVEKLGIAEDEIIVNIQGDEPLIPPAIVRQVAENLAKYQVKMASLAVNITDPEELFNPNAVKVLTDHAGYVLYFSRAP
IPWHRDQFASLPKEKSTRGQLVLSDHYLRHIGIYAYRAGFIKQYIQWQPSVLEQIESLEQLRVLWYGEKIHVELAREVPP
VGVDTAEDLEKVRSILEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-39 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-39 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-39 42