Gene Information

Name : tpx (PM0820)
Accession : NP_245757.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 971188 - 971685 bp
Length : 498 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGAGTAAAATTACATTAGCAGGCACAGAAATTGAAGTTTCAGGTGTATTTCCACAAGTTGGCGATGTAGTTACAGATTT
CACTACGGTGAGTGCAAAATTAGAAGATACGACTTTAGCCAATTTCGCGGGTAAGCGTAAAATTTTAAACATTTTCCCAA
GTATTGATACCGGGATTTGTGCGACATCTGTACGCAAATTCAATGAACAAGCAGCAAAATTAGCGAATACCGCAGTATTA
TGTCTTTCAACGGATTTACCTTTTGCACAAGCACGTTTCTGTGGCGCAGAAGGTCTAGAAAATGTCTTCACGGTATCCAC
TTTCCGCAATAAAGATGTCCACAAACAATTAGGTGTGGATATTGTTGAAGGTCCATTAGCTGGTTTAACCGCCCGTGCAG
TGATCGTATTAGATGAAAATAACCGTGTATTACACAGTGAGTTAGTACCAGAAATCAAACAAGAACCAAATTACGACGCA
GCCTTAGCGGTGCTTTAA

Protein sequence : 
MSKITLAGTEIEVSGVFPQVGDVVTDFTTVSAKLEDTTLANFAGKRKILNIFPSIDTGICATSVRKFNEQAAKLANTAVL
CLSTDLPFAQARFCGAEGLENVFTVSTFRNKDVHKQLGVDIVEGPLAGLTARAVIVLDENNRVLHSELVPEIKQEPNYDA
ALAVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-30 44
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-30 44
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-30 44
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-30 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_245757.1 thiol peroxidase VFG0087 Protein 6e-31 44