Gene Information

Name : alr (PM0413)
Accession : NP_245350.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 484293 - 485375 bp
Length : 1083 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAATATGAAACCTGCCACAGCAAAAATCAGTTCTGTGGCATTAAAACACAACATTCAAACGATTAAACAAAAAGCCCC
GCAAAGTAAAATTATTGCTGTTGTGAAAGCCAACGCCTATGGTCATGGTGTTGTGTTTGTGTCCGCTGCCGTAGAAGAGT
TGGTCGATTGTTTTGGCGTCGCCCGTTTAGAAGAAGCCTTAAGTTTACGCTCAAATGGGATTACGAAACCTATTTTGCTC
TTAGAAGGTTTTTTTTGCGATAAAGATTTACCGGTGATTGCGATAAATAATATTCAAACTGTGGTGCATAACGTCGAACA
ATTGGAAGCGTTAAAAGCAGCTAAAGTTCCTAATCCGATTAAAGTCTGGCTAAAAATTGATACCGGTATGCACCGTTTAG
GGGTAGCACTAGAAGACGTTGAGTATTTTTACCAAGCGCTCCGCGATTCAGAGAATGTTGATCCACAGATTGGTTTTGTC
AGCCATTTTAGTCGCGCGGATGAATTGGAATGTGACTATACCAAGTTACAATTGACACGTTTTTTAAATGCTACGCAAAA
TAAAGCGGGCGAAAAAAGTATTGCTGCCTCAGGTGGGATCTTATTTTGGGAAAGTTCCCATTTAGACTGGATTCGTCCGG
GCATTATTATGTATGGGATTTCACCGATTAATGTACCAGCACAAGAATATGATTTAACCCCTGTGATGACCTTAACCTCC
TCTCTTATTGCAATTAAACAGCATAAAAAAGGGGAGCCAGTAGGATATGGCGGGATTTGGGTCAGCGATAAAGACACGAA
AATTGGTGTGGTTGCCATTGGTTATGGCGATGGTTATCCGCGTGACATACCAACAGGCACACCGGTTTACCTCAATGGTC
GTCGTGTGCCCATTGTGGGACGTGTCTCGATGGATATGTTGACAGTCGATCTCGGTGCAGAAGCACAAGACAAAGTTGGC
GATGAAGTCATTCTTTGGGGCAAAGAATTGCCCATTGAAGAAATCGCGGATATTAGTGGGGTGATTAGTTATGAATTGAT
TACAAAATTAACGCCACGTGTTTTAACGGAATATATTGATTAA

Protein sequence :
MNMKPATAKISSVALKHNIQTIKQKAPQSKIIAVVKANAYGHGVVFVSAAVEELVDCFGVARLEEALSLRSNGITKPILL
LEGFFCDKDLPVIAINNIQTVVHNVEQLEALKAAKVPNPIKVWLKIDTGMHRLGVALEDVEYFYQALRDSENVDPQIGFV
SHFSRADELECDYTKLQLTRFLNATQNKAGEKSIAASGGILFWESSHLDWIRPGIIMYGISPINVPAQEYDLTPVMTLTS
SLIAIKQHKKGEPVGYGGIWVSDKDTKIGVVAIGYGDGYPRDIPTGTPVYLNGRRVPIVGRVSMDMLTVDLGAEAQDKVG
DEVILWGKELPIEEIADISGVISYELITKLTPRVLTEYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 4e-60 41