Gene Information

Name : serS (PM0258)
Accession : NP_245195.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 290295 - 291581 bp
Length : 1287 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGATCCAAATCTATTGCGTAATAATCTTGAGGAAGTGGCTGAAAAATTAAAAGTAAAACGTAATTTTGTGCTAGA
TGTTGCCTTATTAAGTGAATTAGAAGAACAACGTAAAAGCTTGCAAGTCAAAACAGAATCACTTCAAGCAGAACGTAATG
CGCGTTCAAAAAATATCGGCCAAGCGAAAGCACGTGGTGAAGATATTTCAGCATTATTAAACGAAGTGGAACATATGGGC
ATTGAATTAAGTACCACAAAAGCACATTTGGATGAAGTGTTAGCTGAAATTAACCAGATCGTTCTCGCCATTCCAAATTT
ACCTGCTGATGAAGTTCCGCTTGGCAAAGATGAGAGCGAAAATCTCGAAGTGTTCCGTTGGGGAACACCAAAAACCTTTG
ATTTTGATGTGAAAGATCATGTGTCATTAGGTGAAGGTTTGAAAGGGCTAGATTTTGCGGCAGGAGTAAAATTAAGTGGC
TCTCGTTTTGTGGTGATGAAAGGACAGATCGCCAAATTACATCGTGCGCTGTCTCAATTTATGTTAGACCTCCATACTGA
GCAACATGGTTATACCGAAACCTATGTCCCTTATTTAGTTAATCACGCTACTTTATATGGTACCGGGCAATTACCAAAAT
TTGGTGAGGATTTATTTCACACCAATGCGTTAGAAGGCGAACAACCTTATGCATTAATTCCAACAGCAGAAGTACCCGTT
ACGAACTTAGTTCGTGATGAAATTCTCGATGAAGCGGATTTGCCTTTGAAAATGACAGCGCATACTCCTTGTTTCCGTTC
TGAAGCAGGATCCTATGGGCGTGATACCCGCGGTTTAATTCGTATGCATCAATTTGATAAAGTGGAGTTGGTTCAAATTG
TTGCACCTGAAACTTCAATGCAAGTGTTAGAAGAATTGACAGGACAAGCAGAAAAAGTCTTGCAATTATTAGAGTTACCT
TATCGTAAAGTCTTATTATGTACAGGCGATATGGGATTCGGCTCATGCAAGACGTATGACTTAGAAGTATGGTTACCGGC
TCAAAATACCTATCGTGAGATCTCTTCATGTTCAAATATGTGGGATTTCCAAGCTCGTCGCATGCAAGCGCGTTGCCGTT
CTAAAACAGATAAGAAAACACGTTTAGTGCATACTTTAAACGGCTCTGGCTTAGCGGTTGGACGCACTTTGGTCGCGATT
TTAGAAAATTACCAAAATGCAGATGGTACCATTACCGTTCCAAGCGTATTACGTCCATATATGGGCGGGTTAGCACAGAT
TGGTTAG

Protein sequence :
MIDPNLLRNNLEEVAEKLKVKRNFVLDVALLSELEEQRKSLQVKTESLQAERNARSKNIGQAKARGEDISALLNEVEHMG
IELSTTKAHLDEVLAEINQIVLAIPNLPADEVPLGKDESENLEVFRWGTPKTFDFDVKDHVSLGEGLKGLDFAAGVKLSG
SRFVVMKGQIAKLHRALSQFMLDLHTEQHGYTETYVPYLVNHATLYGTGQLPKFGEDLFHTNALEGEQPYALIPTAEVPV
TNLVRDEILDEADLPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVAPETSMQVLEELTGQAEKVLQLLELP
YRKVLLCTGDMGFGSCKTYDLEVWLPAQNTYREISSCSNMWDFQARRMQARCRSKTDKKTRLVHTLNGSGLAVGRTLVAI
LENYQNADGTITVPSVLRPYMGGLAQIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-106 55