Gene Information

Name : smpB (PM0217)
Accession : NP_245154.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 240798 - 241280 bp
Length : 483 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACAAAGAAAAAAGTAAAAGTTGGCACAAATACGATAGCCTTAAATAAACGTGCACGACACGATTATTTTATTGAAGA
CGAAATGGAAGCGGGTCTGGAATTGCAAGGCTGGGAAGTGAAGTCGATGCGTGCTGGAAAAGCCAACATTAGTGACAGTT
ATATTATCTTTAAACAAGGCGAAGCTTATTTATTTGGTGCAACAATTCAGCCACTTAATGTCGCTTCAACGCATATTGTG
TGTGATCCCACACGGACACGCAAGCTGTTACTCAAGCAAAAAGAACTGGCATCATTATTTGGGAAAGCCAATCGTGATGG
CTATACTATCGTTGCTCTCTCACTCTATTGGAAAGGCGCTTGGGCTAAACTGAAAATTGGTCTTGCCAAAGGGAAAAAAC
AGCACGACAAACGTGAAGATATCAAAGAACGCGAGTGGAAAGTCACGAAAGATCGTATTATGAAAAATGCACGCCTTGGC
TAA

Protein sequence :
MTKKKVKVGTNTIALNKRARHDYFIEDEMEAGLELQGWEVKSMRAGKANISDSYIIFKQGEAYLFGATIQPLNVASTHIV
CDPTRTRKLLLKQKELASLFGKANRDGYTIVALSLYWKGAWAKLKIGLAKGKKQHDKREDIKEREWKVTKDRIMKNARLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-41 67
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 4e-17 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-13 42