Gene Information

Name : hemC (PM1812)
Accession : NP_246751.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2041930 - 2042868 bp
Length : 939 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGTTGTGATGATGACAAGAAAAAGCTTGAGAATCGCTACGCGTCAGAGCCCGCTTGCATTGTGGCAAGCGAACTATGT
GAAAGCCTGTTTAGAAAAAATCCATGCTGGATTAGTGGTCGAACTTGTCCCAATGGTGACAAAAGGGGATGTGATTTTAG
ATACGCCACTGGCTAAAATTGGAGGAAAAGGACTCTTTGTGAAAGAGTTAGAACAAGCTTTATTAAAGGGCGAAGCCGAT
ATTGCCGTACATTCGATGAAAGATGTCCCTATGCAGTTTCCAGCAGGATTAATGCTTAGCACCATTTGTCAACGTGAAGA
TCCGCGTGATGCATTTGTATCAAATTCATACCGCACTCTCATGGAATTACCTGCTGGTGCGGTGGTGGGTACCTCTAGCT
TACGTCGCCAATGTCAGTTAAAGCAGTTACGTCCTGATCTACACATTCATTCACTACGTGGCAATGTTGGGACTCGCTTA
GCAAAATTAGATAACGGCGATTATGATGCGATTATTCTGGCTGCCGCGGGGCTTATTCGTTTAGGGCAACAACAACGTAT
CACCTCTTTGATTGATGTCACACAATGTTTACCTGCCGTAGGGCAAGGTGCCGTTGGCATTGAATGTCGTCAAGAAGCAG
AAATTGAGCTGCTGTTAGCCCCTTTAGCCGATCCAGAAACGACTGCTTGTGTATTGGCTGAACGTGCGATGAATCGGCAT
TTACAAGGGGGATGTCAGGTGCCAATTGCAGGTTACGCGATTATCGAAGAGGGACAGCTCTTTTTGCGTGCTTTAGTGGG
CGAAGTAGACGGTTCCAGTATACTTCGTGCAGAAGGACGGAGTGCGGTTGCGGATGCCGAAACATTAGGTATTCAAGTGG
CAGAAAAACTTTTACAGCAAGGTGCGGATAAAATCTTGCAAACACTTTATTCAAACTAA

Protein sequence :
MVVMMTRKSLRIATRQSPLALWQANYVKACLEKIHAGLVVELVPMVTKGDVILDTPLAKIGGKGLFVKELEQALLKGEAD
IAVHSMKDVPMQFPAGLMLSTICQREDPRDAFVSNSYRTLMELPAGAVVGTSSLRRQCQLKQLRPDLHIHSLRGNVGTRL
AKLDNGDYDAIILAAAGLIRLGQQQRITSLIDVTQCLPAVGQGAVGIECRQEAEIELLLAPLADPETTACVLAERAMNRH
LQGGCQVPIAGYAIIEEGQLFLRALVGEVDGSSILRAEGRSAVADAETLGIQVAEKLLQQGADKILQTLYSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-73 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-73 62