Gene Information

Name : PM1712 (PM1712)
Accession : NP_246651.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 1920664 - 1921557 bp
Length : 894 bp
Strand : +
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGCTGTTTAGCATTAGATATTGGTGGAACAAAAATTGCCTCGGCTATTGTAACAGACGGCAAAATAGAACAACGCCA
ACAGATTGCAACGCCACAAGCTGATGCTGCCAATGCGATGCATGACACACTGGCCAACATTCTTGCTTTGTATGCCGGAC
AATTCGATTACGTTGCAGTGGCCTCAACCGGCATTATTAATCATGGTGTGTTAACCGCCTTAAATCCAAAAAATTTAGGT
GGTTTGGCGGAATTTCCCTTAAAAGAAAGCATTGCGCGCCATACGGATAAACCGATTGGTTTACTAAATGATGTGCAAGC
TGCCGCGTGTGCGGAATATAAAGACGAAGATAAAAATGCGGTACAAAATTTTGTTTTTATCACCGTATCCACTGGGGTGG
GTGGTGGCATTATTTTAGAACGCCGTTTATTGACAGAACCTAACGGCGTTGCCGGGCATATCGGACATACATTAGCAGAC
CCAAATGGTCCGGTTTGTGGTTGTGGGCGTGTAGGTTGTGTTGAAGCCGTCGCGGCTGGACGCGCAATTGAAGCCGTTTC
TAGCCAATGGAATCCACCTTGCACACCAAAACAAGCTTTCGAGTTATTTAGAAAAAATGATGAAAAAGCGACCGCACTTA
TCCAGCGTTCAGCTAGCGCGATAGCCAACCTGATTGCGGATTTAGTGATTGGTTTAGATGTACAAAAAGTGGTAGTTGGC
GGTAGTGTTGGTTTAGCGGAAGGTTACCTCCCCTTAGTCAAACAGTACCTCAACATGATGCCACATTTCTATCATTGTAC
CGTTGAACAAGCACGTCACGGACAAGATGCTGGGCTACTGGGTGCCGCTTGGTGGGTAGCCGATTGCCTAAAACAAGGCG
TTCATTTGAAATAG

Protein sequence : 
MRCLALDIGGTKIASAIVTDGKIEQRQQIATPQADAANAMHDTLANILALYAGQFDYVAVASTGIINHGVLTALNPKNLG
GLAEFPLKESIARHTDKPIGLLNDVQAAACAEYKDEDKNAVQNFVFITVSTGVGGGIILERRLLTEPNGVAGHIGHTLAD
PNGPVCGCGRVGCVEAVAAGRAIEAVSSQWNPPCTPKQAFELFRKNDEKATALIQRSASAIANLIADLVIGLDVQKVVVG
GSVGLAEGYLPLVKQYLNMMPHFYHCTVEQARHGQDAGLLGAAWWVADCLKQGVHLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 6e-26 48
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 9e-23 44
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 9e-23 44
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 3e-22 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PM1712 NP_246651.1 N-acetylmannosamine kinase VFG1115 Protein 4e-23 44