Gene Information

Name : tkt_1 (PM1242)
Accession : NP_246179.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1434539 - 1436545 bp
Length : 2007 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGCAACACGTAGAGAACTGGCAAATGCCATTCGTTTTTTAAGTATGGATGCGGTGCAAAAAGCAAAATCAGGGCATCC
AGGTGCACCGATGGGGATGGCAGATATTGCAGAAGTCTTATGGCGTGACTTTTTAAAACATAACCCAAGCAATCCACACT
GGGCCGATCGCGACCGTTTCATTTTATCCAATGGTCATGGTTCAATGCTGATTTACAGTTTATTACATTTAAGTGGTTAT
GACCTTTCTATTGAAGATTTAAAACAATTCCGTCAATTACATTCCAAAACACCGGGACACCCAGAATACGGTTATGCGCC
GGGTGTTGAAACCACAACAGGACCATTAGGTCAAGGGATTACGAACGCAGTGGGTTTTGCGATTGCGGAGAAAACCCTTG
CCCATCAATTTAACCGTCCAGGTCATGAAATTGTTGACCACCACACCTATGTGTTCTTAGGCGATGGTTGTTTAATGGAA
GGGATTTCTCATGAAGCCTGTTCTTTAGCGGGTACTCTTGGGTTAGGTAAATTAATTGCTTTCTATGACGACAACAATAT
CTCAATTGATGGTCATGTGGACGGTTGGTTCACTGATGATACGCAAAAACGGTTTGAAGCTTATGGTTGGCATGTCATTC
CAGCGGTAGATGGTCATAATCCAGAACAAATTCTTGAGGCGGTGAAACAAGCCCAAGCGGAGACAACCAAACCAACCTTA
ATTATTTGTAAAACCATTATCGGTTATGGTTCACCGAATAAAGCCAACTCACACGATTGTCATGGTGCTCCATTAGGTGA
TGATGAAATTGCGGCAGCACGTGAATTCTTAAAATGGGAGCATGCCCCGTTTGAAATTCCTGCGGAGATTTATGCACAAT
GGGATGCGAAAGAAAAAGGTCAAGTTGCTGAAAAAGCGTGGGAAGAAAAATTGGCAGCTTATGCCAAAGCTTACCCAGAA
TTAGCGGCGGAATTTACTCGTCGTGTGAATGCGGAGCTACCGGCAAACTGGGCGGCAGAATCGCAAGCTTTTATTGAACA
TTTACAAGCGAATCCGGCGAACATTGCCAGCCGTAAAGCGTCACAAAATGCGATTGAAGCCTATGCTAAATTATTACCGG
AGTTTTTAGGTGGGTCAGCGGATTTAGCCAGCTCAAACTTAACCCTCTGGTCAGGTTCCAAACCAATCCGTGCGGTAGAA
AATGCCGATGGTAACTACATCAACTACGGTGTGCGTGAGTTTGGTATGTCGGCGATTATGAACGGTATTGCGTTACATGG
TGGTTTCATTCCTTATGGTGCCACTTTCTTGATGTTTATGGAATACGCACATAATGCGGTGCGTATGGCGGCGTTAATGA
AACAACGCTCATTGTTTGTTTATACTCACGACTCTATTGGGCTTGGTGAAGACGGTCCAACTCACCAACCGGTTGAACAA
ACGTCTGCTTTACGTTTAATTCCAAATTTGGAAACATGGCGCCCATGTGACCAAGTGGAATCGGCGGTGGCGTGGAAAGC
GGCAGTGGAACGTAAAGAGGGACCTAGTGCGTTAATTTTTACTCGTCAAAATCTTGCGCAAATGGACCGCACTGCTGAGC
AGTTAGCCAATGTGGCACGTGGTGGTTATGTATTACGTCATTGCTGTGAAAACCAAAACTGTCCAGATTTAATTTTGATT
GCGACCGGTTCTGAGGTGGAATTGGCGATGAAAGCGGCGGATGTTTTAGATGCAGAAGGGGTAAAAGTACGTGTTGTCTC
TATGCCGAGCACCAATGTGTTTGATAAACAAGATGCGGCTTACCGTGAAAGTGTGTTACCAAGCCACATAACAAAACGTG
TTGCGATTGAAGCGGGTATTGCGGACTTCTGGTACAAATATGTGGGCTTTGAGGGACGTGTTGTGGGAATGAACAGTTTT
GGTGAATCCGCACCAGCTGACCAATTGTTCAAACTCTTTGGTTTTACAGTCGAGAATATAGTCGAAAAAGCAAAAGCGAT
TTTATAA

Protein sequence :
MATRRELANAIRFLSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPSNPHWADRDRFILSNGHGSMLIYSLLHLSGY
DLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGFAIAEKTLAHQFNRPGHEIVDHHTYVFLGDGCLME
GISHEACSLAGTLGLGKLIAFYDDNNISIDGHVDGWFTDDTQKRFEAYGWHVIPAVDGHNPEQILEAVKQAQAETTKPTL
IICKTIIGYGSPNKANSHDCHGAPLGDDEIAAAREFLKWEHAPFEIPAEIYAQWDAKEKGQVAEKAWEEKLAAYAKAYPE
LAAEFTRRVNAELPANWAAESQAFIEHLQANPANIASRKASQNAIEAYAKLLPEFLGGSADLASSNLTLWSGSKPIRAVE
NADGNYINYGVREFGMSAIMNGIALHGGFIPYGATFLMFMEYAHNAVRMAALMKQRSLFVYTHDSIGLGEDGPTHQPVEQ
TSALRLIPNLETWRPCDQVESAVAWKAAVERKEGPSALIFTRQNLAQMDRTAEQLANVARGGYVLRHCCENQNCPDLILI
ATGSEVELAMKAADVLDAEGVKVRVVSMPSTNVFDKQDAAYRESVLPSHITKRVAIEAGIADFWYKYVGFEGRVVGMNSF
GESAPADQLFKLFGFTVENIVEKAKAIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 77
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68