Gene Information

Name : leuS (PM1214)
Accession : NP_246151.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1405076 - 1407658 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAACAATACCGTCCCGATTTGATTGAAGCGGAAGTTCAACAATACTGGGCTGAAAATAAAACATTTAAAGCGAT
TAAAGATACTAATAAACCGAAATATTACTGCCTCTCAATGTTCCCTTACCCCTCTGGTCGTCTGCACATGGGACATGTGC
GTAACTACACCATTGGTGATGTGGTGTCACGTTATCAACGTATGAACGGCAAAAATGTGTTACAACCGATGGGCTGGGAC
GCTTTTGGTTTGCCCGCAGAAGGCGCAGCGATCAAAAACAAAACGGCACCCGCAAAATGGACTTACGAGAATATTGATTA
TATGAAAAATCAGCTCAAAATTTTGGGCTTTGGTTTTGACTGGGATCGTGAAGTGACCACCTGTAAACCCGACTACTACA
AATGGGAACAATGGTTCTTCACTGAGTTATATAAAAAAGGATTAGTGTACAAAAAAACCTCAACAGTAAACTGGTGTCCA
AATGATGAAACTGTCTTAGCCAACGAACAAGTGCATGAAGGTTGCTGCTGGCGTTGTGATACCCCAGTAGAACAAAAAGA
AATTCCACAATGGTTTATCAAAATCACAGATTATGCCGAACAATTATTAGGCGGGTTAGATCACCTTCCATTATGGCCAG
ATCAAGTAAAAACCATGCAACGTAACTGGATCGGGCGTTCTGAAGGGGTGGAAATCACCTTCCAGTTAGCCAATTCAGAA
GACAATTTAACCGTTTATACGACACGTCCAGATACTTTCTTTGGCGTCTCTTATGTGGCCGTGGCAGCTGCACATCCTTT
AGCAGAAAAAGCGGCAGAAAATAATCCTGAATTAGCTCAATTTATTCAAGAATGCAAAAATACCAAAGTGGCTGAAGCTG
AGCTTGCCACAATGGAGAAAAAAGGCATGGCGACTGGTGTGTATGCCATTCATCCATTAACGGGGGAAAAAGTGCCGGTC
TGGGTGGCTAACTTTGTGTTAATGCACTACGGTACAGGGGCTGTAATGGCAGTGCCTGGACACGATGAACGTGATGCTGA
GTTCGCTCGTAAATATGGTTTACCACTGCTTAATGTCATTAAGCCGATTAATGGTGAGCCTTTACTTGAACATGAATTAC
CTTATTGTGAGCATGGTATTTTGTTTAATTCAGGTGAATTTAATGGTCTAGACTTTGATGCCGCATTTAATGCGATCGCA
GACAAATTAGAAGCGCTTGGCAAAGGAAAACGTCAAGTGAATTACCGCTTACGTGACTGGGGTGTTTCTCGTCAACGTTA
CTGGGGAGCGCCAATTCCAATGCTTACCTTAGAAAATGGTGAGGTGGTGCCTGCGCCATTGCAAGATCTGCCAATCGAAT
TACCAGAAGATGTGGTGATGGACGGCGTGAAAAGTCCAATTAAAGCCGATCCAGAATGGGCAAAAACCACTTACAACGGT
CAGCCAGCACTGAAAGAAACGGATACCTTTGATACTTTCATGGAATCCTCATGGTATTACGCCCGTTATACCTCACCAAA
ATTTGCGGAAGCCATGTTAGATGCGGACGAAGCAAACTATTGGTTACCGGTGGATCAATACATTGGTGGCATTGAGCATG
CGACGATGCACTTGTTGTACTTCCGTTTCTTCCACAAATTATTGCGTGATGCAGGTTTTGTCACGAGCGATGAGCCCGCA
GATAAATTATTGTGCCAAGGCATGGTGTTAGCCGATGCATTCTACTACACCTCACCAACCAATGAGCGTATTTGGGTGTC
CCCAACAGAAGTCACTCTTGAGCGTGATGAGAAAGGGCGCATCCTGAAAGCCTTTGATAAAGAAGGACGAGAACTAGTGC
ATTCTGGTATGACTAAAATGTCTAAATCGAAAAATAACGGGATTGACCCACAAGAAATGGTGGAAAAATACGGTGCGGAT
ACCGTACGTTTATTCATGATGTTCGCTTCACCAGCAGAAATGACCCTTGAATGGCAAGAATCAGGCGTCGAAGGAGCAAA
ACGTTTCTTGGGACGTTTATGGAATCTCGTGTTTGAATATAACAAACATCCCGCAGAAACTACCGTAGAACCGACCGCAC
TTTCAAGCGCACAAAAAGCTTTACGTCGTGATGTACACAAAACGATTGCTAAAGTGAGTGATGATATCGGTCGTCGTCAA
ACCTTCAATACTGCCATTGCCGCGATTATGGAGTTAATGAATAAATTAACCAAAGCGCCATTAGTGGAAGTACAAGATCG
CGCGATTATGGCAGAAGCATTAAGTGCCGTCGTACGTATGCTTTACCCAATCACACCACATATTTGTTTCCAATTATGGA
AAGACTTAGGTAATACAGAAGCGATTGACTTTGCCCCTTGGGTAGAAGCCGATGCAGCAGCGATGGTTGACGATGAAAAA
TTGGTTGTGGTACAAGTGAATGGTAAAGTGCGTGCCAAAGTGACCGTCCCTGCAGAAATGTCAGAAGACGATATCAAGCA
AGTCGCATTAGCAGATAGCAATGTAGCCAAACACTTAGAAGGTTTAAACATTGTGAAAACCATCTATGTACCGGGAAAAT
TATTTAGCTTTGTGGCAAAATAA

Protein sequence :
MQEQYRPDLIEAEVQQYWAENKTFKAIKDTNKPKYYCLSMFPYPSGRLHMGHVRNYTIGDVVSRYQRMNGKNVLQPMGWD
AFGLPAEGAAIKNKTAPAKWTYENIDYMKNQLKILGFGFDWDREVTTCKPDYYKWEQWFFTELYKKGLVYKKTSTVNWCP
NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLGGLDHLPLWPDQVKTMQRNWIGRSEGVEITFQLANSE
DNLTVYTTRPDTFFGVSYVAVAAAHPLAEKAAENNPELAQFIQECKNTKVAEAELATMEKKGMATGVYAIHPLTGEKVPV
WVANFVLMHYGTGAVMAVPGHDERDAEFARKYGLPLLNVIKPINGEPLLEHELPYCEHGILFNSGEFNGLDFDAAFNAIA
DKLEALGKGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGEVVPAPLQDLPIELPEDVVMDGVKSPIKADPEWAKTTYNG
QPALKETDTFDTFMESSWYYARYTSPKFAEAMLDADEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPA
DKLLCQGMVLADAFYYTSPTNERIWVSPTEVTLERDEKGRILKAFDKEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRLWNLVFEYNKHPAETTVEPTALSSAQKALRRDVHKTIAKVSDDIGRRQ
TFNTAIAAIMELMNKLTKAPLVEVQDRAIMAEALSAVVRMLYPITPHICFQLWKDLGNTEAIDFAPWVEADAAAMVDDEK
LVVVQVNGKVRAKVTVPAEMSEDDIKQVALADSNVAKHLEGLNIVKTIYVPGKLFSFVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-152 41