Gene Information

Name : metB (PM0995)
Accession : NP_245932.1
Strain : Pasteurella multocida Pm70
Genome accession: NC_002663
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1168033 - 1169142 bp
Length : 1110 bp
Strand : -
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGACACAACATTATTCAATTGAAACGTTATTAGCGCAGGCTGGAAATCGAACGGATGAGCGTACTGGTGCAGTTTCTAC
ACCGATCTTTTTATCAACAGCTTATGCCCACCATGGAATTGGTGAAAGTACAGGCTATGACTATACACGTACGAAAAATC
CAACACGTAGCGTTTTAGAAGAAACCATTGCTAAATTAGAAGGTGGGGAACGAGGCTTTGCTTGTGCTTCAGGAATGGCG
GCAATTCAATTAATCATGTCCTTATTTACGTCCCCTGATGAGTGGATTGTTTCGCGTGATGTGTATGGTGGCACCTATCG
TTTATTGGATTTCGCGTACAAAAATACACAAGGCGTTAAACCAGTTTATGTGAATACATCAGAGGTATCCTGTATCGAAG
CGGCGATTACGTCTAATACAAAAGCAATTTTTGTAGAAACTCCTTCTAATCCTTTGATGGAGGAATGTGATGTAGCTGCG
ATTGCAAAAATTGCGAAAAAACATAATCTGCTTTTGATTGTCGATAATACTTTCTTAACACCGGTTTTATTTAGACCAAT
TGAGGCTGGTGCAGATATTGTGATTCATAGTGGAACTAAATACTTGGCTGGTCATAACGATGCTTTGGTTGGACTGGTTG
TGGCAAAAGGTGAAGAACTCTGCCAACGTTTATTCTATATTCAGAATGGGGCAGGTGCAGTTCTGTCGCCTTTCGATTCA
TGGTTAACGATTCGAGGCATGAAAACCCTCGCCTTACGTATGGAACGTCATGAACAAAATGCCAAACAGCTGGCTGCGTT
TCTGGCTTCTCAGCCACAAGTAAAAAATGTGTTATATCCAAATAAGGGCGGTATGCTTTCTTTCCGCTTACATGAAGCAC
ATTGGGTTAATCCTTTTTTGAAAGCGCTGAAACTAATCACTTTTGCTGAAAGTTTGGGGGGAACAGAGAGCTTTATTACT
TATCCAGCGACACAAACCCATATGGATATTCCAGAAGAGGAGCGTATTGCGCGCGGTGTGTGTAATTGTCTTTTGCGTTT
TTCTGTTGGTTTAGAAAATGTAGAGGATATTAAAGCGGATTTATTACAAGCGTTTGCACAATTAAACTAA

Protein sequence :
MTQHYSIETLLAQAGNRTDERTGAVSTPIFLSTAYAHHGIGESTGYDYTRTKNPTRSVLEETIAKLEGGERGFACASGMA
AIQLIMSLFTSPDEWIVSRDVYGGTYRLLDFAYKNTQGVKPVYVNTSEVSCIEAAITSNTKAIFVETPSNPLMEECDVAA
IAKIAKKHNLLLIVDNTFLTPVLFRPIEAGADIVIHSGTKYLAGHNDALVGLVVAKGEELCQRLFYIQNGAGAVLSPFDS
WLTIRGMKTLALRMERHEQNAKQLAAFLASQPQVKNVLYPNKGGMLSFRLHEAHWVNPFLKALKLITFAESLGGTESFIT
YPATQTHMDIPEEERIARGVCNCLLRFSVGLENVEDIKADLLQAFAQLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-67 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-67 42