Gene Information

Name : pdhD (L0036)
Accession : NP_266215.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 58971 - 60389 bp
Length : 1419 bp
Strand : -
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGTTGTTGGTGCACAAGCAACAGAAGTTGATTTGGTTGTTATTGGTTCAGGCCCTGGTGGTTATGTTGCAGCCATCCG
TGCGGCTGAACTTGGTAAAAAAGTTACAATTATTGAAAAAGATAATGTTGGTGGGGTTTGTTTAAATATTGGTTGTATCC
CATCAAAAGCATTGATTAATATTGGTCATCATTACCAAGAATCTTTGGAGGAAGAAAAAGGAGAAAATCCTTTTGGTCTT
TCTGTCGGAAATGTTAAATTAAACTGGGAATCTGCCCAAAAATGGAAACAAGATAAAGTTGTCAACCAGTTGACAGGTGG
TGTTAAAATGCTACTTAAAAAACACAAAGTTGACGTGATTCAAGGAACTGCAGAATTTATTGATAACAATACAATAAATG
TTGAACAAGAAGATGGGTTCCAACTTTTGCAATTTAATGATGTGATTATCTCAACTGGTTCACGTCCTATCGAAATTCCT
TCTTTCCCATTTGGTGGTCGCATTATTGACTCTACTGGTGCTTTGTCACTTCCAGAAGTTCCTAAACATTTGATTATTGT
TGGGGGAGGAGTTATTGGTTCTGAGCTTGGTGGAGCATACCGTATGCTCGGTTCTAAGATTACAATTGTTGAAGGTTTGG
ACCACATTTTAAACGGGTTTGATAAAGAAATGTCTGATATCATTGCTAATCGCGTTAAATCTGCTGGTTCTGAAATCTTT
ACTTCAGCAATGGCTAAATCAGCTACTCAAACTGATAAAGATGTAACTTTGACTTTTGAGGTTGACGGAAAAGAACAAAC
GGTGACTGGTGATTACTTACTCGTTTCTGTTGGACGTCGTCCAAATACTGATTTAATCGGCTTGAACAACACTGATGTTA
AATTGACTGACCGTGGTTTGATTGAAGTTGACGATTCTTATGCAACTAATGTTCCTCACATTTATGCAATCGGTGATGTG
GTTCCTGGTCCAATGCTCGCTCACAAAGCTTCTTTCCAAGCTAAAGTTGCTGCTGCTGCGATTGCTGGAGCTGAGGACGA
CGTGGACTTACACGTTGCTTTGCCTGCTGTAGCTTATACAACAACTGAATTAGCAACAGTTGGAGAAACGCCTGAATCAG
TTAAAGACCGTAAAGATGTTAAAATTTCTAAGTTCCCATTTGCTGCAAATGGCCGTGCCATTTCAATGAATGATACGACT
GGTTTCTTACGTTTGATTACTGAAACTAAAGAAGGGGCCTTAATCGGTGCTCAAATCGTTGGCCCTGGTGCATCTGACTT
GATTTCTGGTTTATCACTAGCGATTGAAAATGGATTGACTTCTAAAGACATTTCATTGACTATCCAACCTCACCCAACAC
TTGGTGAAGCGATTATGGATACAGCTGAATTGGCTGATGGCTTACCAATTCACGTTTAA

Protein sequence :
MVVGAQATEVDLVVIGSGPGGYVAAIRAAELGKKVTIIEKDNVGGVCLNIGCIPSKALINIGHHYQESLEEEKGENPFGL
SVGNVKLNWESAQKWKQDKVVNQLTGGVKMLLKKHKVDVIQGTAEFIDNNTINVEQEDGFQLLQFNDVIISTGSRPIEIP
SFPFGGRIIDSTGALSLPEVPKHLIIVGGGVIGSELGGAYRMLGSKITIVEGLDHILNGFDKEMSDIIANRVKSAGSEIF
TSAMAKSATQTDKDVTLTFEVDGKEQTVTGDYLLVSVGRRPNTDLIGLNNTDVKLTDRGLIEVDDSYATNVPHIYAIGDV
VPGPMLAHKASFQAKVAAAAIAGAEDDVDLHVALPAVAYTTTELATVGETPESVKDRKDVKISKFPFAANGRAISMNDTT
GFLRLITETKEGALIGAQIVGPGASDLISGLSLAIENGLTSKDISLTIQPHPTLGEAIMDTAELADGLPIHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 5e-78 45