Gene Information

Name : hsdM (L0309)
Accession : NP_266807.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : type I restriction enzyme M protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 3.1.21.3
Position : 643807 - 645354 bp
Length : 1548 bp
Strand : +
Note : -

DNA sequence :
ATGGCATTATCAAATGAACAAAAAAATAAAATGTGGGCCCTCTTAAATCAAACCCGAGGACAGATTGGTTTAACCGCCTA
TAAAGACTACATTTTTGGCTTACTATTTTATAAATATTTATCAGAAAAGGCCACACAATGGCTGGGAGAAGTTTTACGAG
GAGACACTTGGGAAAATGTTTATGATCAAGATCCTGTAAGAGCCTTAGACTATATGAAACAAAAGCTCGGTTATGCCATC
CAACCGAAGGAATTTTTTAAAGATTGGGAAGCTGCCATTCATGAAGAACGATTTAACATTCCAATGATTTCAGATACATT
TGGCCATTTTAATCAGCAAATTGCTTTTGAAGCTAAAGATGATTTTGAAGGCATCTTTGATGGGATGCGTTTTGATAGTT
CAGATTTAGGAAGTAATGCGCAAGCTCGAGCAAGTGTGATGATCTCGATGATTGAGTTACTCTCTGCCCCTGAGTTTGAT
CTCTCTACAGGAGGGGACACCGTTTCAGATATCTACGAATACTTGTTAGAAAAGTTTGCGACCGTATTGGCCTCAGACAT
GGGACAATACTATACTCCCAAAGAAATTTCAGAGGTCATGGCTCGTATTTTGACTTTTGGTAAAGCCGACGAAGACAATT
TTTCTATTTATGATCCCGCGGTCGGTTCAGCTTCTCTCTTAATTACTACCGCCAGTCATATGAAACATTCCAATCAAAGG
GGAGCGATTAAATACTTTGGTCAAGAAAAAGATGCCACCCCTTACCGATTGGCTCGAATGAATTTAATGATGCATAACAT
TGAATACAATGATATTCAGATCCATCATGCGGATACTTTGGAAAGCGATTGGCCTGACGGAGTCATTGAAGGGAAAGATA
CGCCTCGAATGTTTGACGCAGTGATGGCTAATCCACCTTATTCTGCCCATTGGAATAATAAGGATCGGGAAGATGACCCT
CGATTTCGTGAATATGGCATTGCGCCAAAAACTAAAGCGGACTATTCTTTCTTGTTGCATTGTTTGTACCATACCAAAGA
GAGTGGCCGTGTGGCCATTATTCTCCCACACGGGGTCTTGTTTAGAGGCGCTGCGGAAGGACGGATTCGAAAAGCTTTGA
TTGATAAACATCAAATTGAAGCGGTAATTGGTTTTCCAGATAAACTCTTTTTGAACACAGGCATTCCCGTTTGTGTCTTA
ATTCTTAAAAAGAATCGAGCAAACTCTGATATTCTTTTTGTGGACGCCAGTCAAGGCTTTGAAAAGATGAAGAATCAAAA
ACAATTGCGCCCAGAAGATATTGACAAGATCACTGAAACAGTCATTCATCGCAAGGCGGTTGATAAATATAGCCACTTAG
CAACGCTTGAGGAAGTCATTGAGAATGATTACAACTTAAATATTCCGCGTTATGTGGATACCTTTGAAGAGGAAGAATCG
ATTGACTTAGCGGATATTCAAGGTCAAATAGATGAAGTAGACGCAGAGATTGCGAAAGCTAATCAAACCTTAGCAAACTA
CTTTAAGGAACTGGGAGTGCTAAAATGA

Protein sequence :
MALSNEQKNKMWALLNQTRGQIGLTAYKDYIFGLLFYKYLSEKATQWLGEVLRGDTWENVYDQDPVRALDYMKQKLGYAI
QPKEFFKDWEAAIHEERFNIPMISDTFGHFNQQIAFEAKDDFEGIFDGMRFDSSDLGSNAQARASVMISMIELLSAPEFD
LSTGGDTVSDIYEYLLEKFATVLASDMGQYYTPKEISEVMARILTFGKADEDNFSIYDPAVGSASLLITTASHMKHSNQR
GAIKYFGQEKDATPYRLARMNLMMHNIEYNDIQIHHADTLESDWPDGVIEGKDTPRMFDAVMANPPYSAHWNNKDREDDP
RFREYGIAPKTKADYSFLLHCLYHTKESGRVAIILPHGVLFRGAAEGRIRKALIDKHQIEAVIGFPDKLFLNTGIPVCVL
ILKKNRANSDILFVDASQGFEKMKNQKQLRPEDIDKITETVIHRKAVDKYSHLATLEEVIENDYNLNIPRYVDTFEEEES
IDLADIQGQIDEVDAEIAKANQTLANYFKELGVLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 2e-94 41
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 1e-95 41
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 3e-94 41