Gene Information

Name : polA (L0270)
Accession : NP_268299.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2210775 - 2213408 bp
Length : 2634 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAGAACAAGGACAGACTTTTACTAATTGATGGGTCATCGGTTGCCTTTCGGGCCTTTTTTGCGCTATATAATCAGAT
AGATCGCTTTAAAGCGCCAAATGGGTTACATACTAATGCTATTTTTGCATTTCATACAATGCTTTCTTCATTGATGGAAC
GGATTGAGCCCACACATGTTTTGATTGCATTTGATGCAGGAAAAACAACTTTTCGTACGGAAATGTTTGCTGACTATAAA
GGTGGACGTTCAAAAACACCAGATGAATTTCGTGAGCAATTACCTTTTATCAAGGAAATGATTGAGAAATTGGGAATTCG
TCATTATGAGTTAGCTAACTATGAGGCTGATGATATTATTGGGACTTTGGACAAAATGGCGGAAGCCCCAAATGTTAATT
TTGATGTTACTATTGTGACGGGTGATAAGGATATGATTCAGCTTGTGGATGGAAATACGCGAGTTGAAATTTCTAAGAAG
GGTGTTGCTGAGTTTGAGGAGTTTACACCTGATTATCTTTTAGAAAAAATGGGATTGACTCCAGCCCAATTTATTGATTT
AAAAGCATTAATGGGCGATTCTTCTGATAATTACCCTGGCGTGACAAAAGTTGGCGAAAAAACTGGCCTTAAACTTTTAC
AAGAGTTTGGGTCGCTTGAAAATCTTTATGAAAATGTTGATTCTTTGAAAGCCAGCAAAATGAAAGAAAATCTAATTGCT
GACAAAGAAATGGCTTTTTTGTCACAACAATTGGCAACGATAAATACGAAAGCTCCAATTGAAATTGGCTTAGATGATAC
GCTTTTAAAAGGTAAAAAGGTTGATGAACTTAGTCAATTTTATGATGAAATGGGATTTGCTCAATTCAAAAGTAAATTAT
TGGCTGAGGCTGGTGGAGAAGTTACTGACGAAAAAGTTGTTGACGAAATTGATTTTGAAATAGTTACTGATGGCTCTATC
AGTGAAAAGGTAAATGCTGATGATTTCTTCTATTTGGAAACTTTAGGGGAAAATTATCATCGTGAGCAAATTGTGGCTTT
TGCCTGGGGAAATGCTGAGAAAATTTATGTTTCTAAAAATATAGATTTACTGACAAAAATGAAGTTCCCTGAAAATACTT
ATGATTTCAAGAAAAATCGGGTACTTTTGAGTCACTTGGATATCGAATTACCTTTGGTCAAATTTGATGCAATGCTTGCA
AAATATCTAATTTCAACAACAGAAGATAATAAAATTTCGACGATTGCAAGACTTTTCAATAGCGGACATTTGGCAACGGA
TGAAGAAATTTTTGGCAAAGGGACAAAAATTGCTTTACCTGATGATGCGGTTTTATTTGAACATTTAGCTCGTAAAATTA
AAGTGCTTGCCTTGGCCAAAGAAAAAATGATGGCTGAATTGCTTGAAAATGAACAAGAGCATCTTTTGTCTGACATGGAA
TTACCATTAGCAGAAGTTTTAGCAAAAATGGAAATTACAGGGATTGCTGTCAGCCAAAATACACTGGAAGAAATTGGTGC
GGAAAATGAAGAAAAATTGGCTTCTTTGACGCGTGAAATTTACGACTTGGCTGGTGAAGAATTTAATATTAATTCACCAA
AACAGTTGGGTGTGATTTTATTTGAAAAATTACAGCTACCGGTTGGAAAGAAAACAAAAACAGGCTATTCAACGGCAGTG
GATGTTTTAGAAGACTTAGCTGCTTTATCTCCGGTTGTAGCAAAAATTTTGGAATATCGTCAAATCAATAAAGTACAATC
AACTTATGTGAAAGGTCTGATTCCTCAAATTGCTGATGATGGAAAAATTCATACACGTTATGTTCAAGATTTGACTCAAA
CTGGACGTTTGAGCTCAGTTGACCCGAATTTACAAAATATTCCTGTTCGACTTGAGGAGGGACGAAAAATTCGTAAAGCA
TTTGTCCCAAGCAAAGATTCGCTTTTATTGAGTTCTGACTATTCACAAATTGAATTGCGGGTTTTGGCACATATTTCTGG
GGATGAACATTTGATTGATGCCTTTAAACATGGAGCTGATATCCATACTTCAACGGCTATGCGTGTTTTCGGCATTGAAA
AAGCAGAAGATGTGACTGCTAATGATCGTAGAAATGCTAAAGCAGTCAATTTTGGAGTAGTCTATGGAATTTCCGATTTT
GGTTTAGCAAGAAATCTTGGAATTACAAGAAAAGATGCTAAAAATTACATTGAAACTTATTTTGAACGTTATCCTGGGAT
TAAAACCTATATGGAAAATATTGTTCGCGAGGCACGAGACAAAGGTTTTGTTGAAACAATGAGTCACCGTCGTCGTAAGA
TTCCAGATATTAATGCTCGTAATTTTAATGTTCGTGGTTTTGCAGAACGGACGGCTATTAATTCACCAATTCAAGGTTCG
GCAGCTGATATCTTAAAAATTGCGATGATTAATTTGGATAAAGCTTTGAGTGCTCGTGATTTTAAATCAAAATTATTATT
GCAAGTACACGATGAAATTATCCTTGATGTTCCTTTAGAGGAATTAGATGAAATTAAGGTCTTGGTAAAACAAACGATGG
AAGAAGCGATTGAACTTGCTGTCCCATTAAAAGTGGATGAAAATACTGGTAAGACTTGGTATGAAGCTAAATAA

Protein sequence :
MENKDRLLLIDGSSVAFRAFFALYNQIDRFKAPNGLHTNAIFAFHTMLSSLMERIEPTHVLIAFDAGKTTFRTEMFADYK
GGRSKTPDEFREQLPFIKEMIEKLGIRHYELANYEADDIIGTLDKMAEAPNVNFDVTIVTGDKDMIQLVDGNTRVEISKK
GVAEFEEFTPDYLLEKMGLTPAQFIDLKALMGDSSDNYPGVTKVGEKTGLKLLQEFGSLENLYENVDSLKASKMKENLIA
DKEMAFLSQQLATINTKAPIEIGLDDTLLKGKKVDELSQFYDEMGFAQFKSKLLAEAGGEVTDEKVVDEIDFEIVTDGSI
SEKVNADDFFYLETLGENYHREQIVAFAWGNAEKIYVSKNIDLLTKMKFPENTYDFKKNRVLLSHLDIELPLVKFDAMLA
KYLISTTEDNKISTIARLFNSGHLATDEEIFGKGTKIALPDDAVLFEHLARKIKVLALAKEKMMAELLENEQEHLLSDME
LPLAEVLAKMEITGIAVSQNTLEEIGAENEEKLASLTREIYDLAGEEFNINSPKQLGVILFEKLQLPVGKKTKTGYSTAV
DVLEDLAALSPVVAKILEYRQINKVQSTYVKGLIPQIADDGKIHTRYVQDLTQTGRLSSVDPNLQNIPVRLEEGRKIRKA
FVPSKDSLLLSSDYSQIELRVLAHISGDEHLIDAFKHGADIHTSTAMRVFGIEKAEDVTANDRRNAKAVNFGVVYGISDF
GLARNLGITRKDAKNYIETYFERYPGIKTYMENIVREARDKGFVETMSHRRRKIPDINARNFNVRGFAERTAINSPIQGS
AADILKIAMINLDKALSARDFKSKLLLQVHDEIILDVPLEELDEIKVLVKQTMEEAIELAVPLKVDENTGKTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 70